Human stem cell models for Marfan syndrome: a brief overview of the rising star in disease modelling

Human stem cell models for Marfan syndrome: a brief overview of the rising star in disease modelling

The introduction of pluripotent stem cells into the field of disease modelling resulted in numerous opportunities to study and uncover disease mechanisms in a petri dish. This promising avenue has also been applied to model Marfan syndrome, a disease affecting multiple organ systems, including the s...

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Bibliographic Details
Main Authors: Jeffrey Aalders, Laura Muiño Mosquera, Jolanda van Hengel
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
human pluripotent stem cells
Marfan syndrome
disease modelling
in vitro
aortopathy
cardiomyopathy
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2024.1498669/full
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