Iron oxide Nanoparticles; A Review on the role of Transition Metal doping on its magnetic properties and particle size for imaging and therapeutic applications
Iron oxide nanoparticles (IO-NPs) are one of the remarkable materials for diagnostic and therapeutic applications. However, its applications are still facing a good number of challenges. Hence, there is growing interest in modifying IO-NPs properties to enhance their applicability. In this review, t...
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| Format: | Article |
| Language: | English |
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Elsevier
2024-12-01
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| Series: | Hybrid Advances |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2773207X24001830 |
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| author | Izunna Stanislaus Okeke Eugene Odinakachi Echeweozo Amoge Chidinma Ogu Priscilla Yahemba Aondona Fabian I. Ezema |
| author_facet | Izunna Stanislaus Okeke Eugene Odinakachi Echeweozo Amoge Chidinma Ogu Priscilla Yahemba Aondona Fabian I. Ezema |
| author_sort | Izunna Stanislaus Okeke |
| collection | DOAJ |
| description | Iron oxide nanoparticles (IO-NPs) are one of the remarkable materials for diagnostic and therapeutic applications. However, its applications are still facing a good number of challenges. Hence, there is growing interest in modifying IO-NPs properties to enhance their applicability. In this review, the effect of Transition Metal (TM) doping on the IO-NPs magnetic properties and particle sizes as well as its role in IO-NPs imaging and therapeutic applications was discussed.Reviewed articles show that doping IO-NPs with TM alters their magnetic properties and particle size. In imaging, this had led to significant effects on IO-NPs relaxometric parameters and ultimate improvement in image contrasts in MRI. Gold-doped IO-NPs indicated improved performance in tumor catalytic and x-ray radiation therapy. Furthermore, research findings revealed that TM provides the opportunity for temperature control in IO-NPs hyperthermia application. The findings from the reviewed papers suggest that TM doped IO-NPs can be critical in enhancing applications of IO-NPs in hyperthermia, drug delivery diagnostics, and therapeutics. |
| format | Article |
| id | doaj-art-27604df83437456db596928e95fb2abb |
| institution | OA Journals |
| issn | 2773-207X |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Hybrid Advances |
| spelling | doaj-art-27604df83437456db596928e95fb2abb2025-08-20T01:54:54ZengElsevierHybrid Advances2773-207X2024-12-01710032210.1016/j.hybadv.2024.100322Iron oxide Nanoparticles; A Review on the role of Transition Metal doping on its magnetic properties and particle size for imaging and therapeutic applicationsIzunna Stanislaus Okeke0Eugene Odinakachi Echeweozo1Amoge Chidinma Ogu2Priscilla Yahemba Aondona3Fabian I. Ezema4Department of Physics and Astronomy, Faculty of Physical Sciences, University of Nigeria Nsukka, Obukpa Rd, Nsukka, Enugu, Nigeria; Corresponding author.Department of Physics with Electronics, Faculty of Physical Sciences, Evangel University, Akaeze, Ebonyi, NigeriaDepartment of Medical Biotechnology, National Biotechnology Development Agency, Lugbe, FCT Abuja, NigeriaDepartment of Medical Biotechnology, National Biotechnology Development Agency, Lugbe, FCT Abuja, NigeriaDepartment of Physics and Astronomy, Faculty of Physical Sciences, University of Nigeria Nsukka, Obukpa Rd, Nsukka, Enugu, Nigeria; Nanosciences African Network (NANOAFNET), iThemba LABS-National Research, 1 Old Faure Road, 7129, P.O. Box 722, Somerset West, Western Cape Province, South Africa; UNESCO-UNISA Africa Chair in Nanosciences/Nanotechnology, College of Graduate Studies, University of South Africa (UNISA), Muckleneuk ridge, P.O. Box 392, Pretoria, South AfricaIron oxide nanoparticles (IO-NPs) are one of the remarkable materials for diagnostic and therapeutic applications. However, its applications are still facing a good number of challenges. Hence, there is growing interest in modifying IO-NPs properties to enhance their applicability. In this review, the effect of Transition Metal (TM) doping on the IO-NPs magnetic properties and particle sizes as well as its role in IO-NPs imaging and therapeutic applications was discussed.Reviewed articles show that doping IO-NPs with TM alters their magnetic properties and particle size. In imaging, this had led to significant effects on IO-NPs relaxometric parameters and ultimate improvement in image contrasts in MRI. Gold-doped IO-NPs indicated improved performance in tumor catalytic and x-ray radiation therapy. Furthermore, research findings revealed that TM provides the opportunity for temperature control in IO-NPs hyperthermia application. The findings from the reviewed papers suggest that TM doped IO-NPs can be critical in enhancing applications of IO-NPs in hyperthermia, drug delivery diagnostics, and therapeutics.http://www.sciencedirect.com/science/article/pii/S2773207X24001830Iron oxides nanoparticlesTransition metalsMagnetic propertiesParticle sizeTheranostics |
| spellingShingle | Izunna Stanislaus Okeke Eugene Odinakachi Echeweozo Amoge Chidinma Ogu Priscilla Yahemba Aondona Fabian I. Ezema Iron oxide Nanoparticles; A Review on the role of Transition Metal doping on its magnetic properties and particle size for imaging and therapeutic applications Hybrid Advances Iron oxides nanoparticles Transition metals Magnetic properties Particle size Theranostics |
| title | Iron oxide Nanoparticles; A Review on the role of Transition Metal doping on its magnetic properties and particle size for imaging and therapeutic applications |
| title_full | Iron oxide Nanoparticles; A Review on the role of Transition Metal doping on its magnetic properties and particle size for imaging and therapeutic applications |
| title_fullStr | Iron oxide Nanoparticles; A Review on the role of Transition Metal doping on its magnetic properties and particle size for imaging and therapeutic applications |
| title_full_unstemmed | Iron oxide Nanoparticles; A Review on the role of Transition Metal doping on its magnetic properties and particle size for imaging and therapeutic applications |
| title_short | Iron oxide Nanoparticles; A Review on the role of Transition Metal doping on its magnetic properties and particle size for imaging and therapeutic applications |
| title_sort | iron oxide nanoparticles a review on the role of transition metal doping on its magnetic properties and particle size for imaging and therapeutic applications |
| topic | Iron oxides nanoparticles Transition metals Magnetic properties Particle size Theranostics |
| url | http://www.sciencedirect.com/science/article/pii/S2773207X24001830 |
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