3‐HKA Promotes Vascular Remodeling After Stroke by Modulating the Activation of A1/A2 Reactive Astrocytes

3‐HKA Promotes Vascular Remodeling After Stroke by Modulating the Activation of A1/A2 Reactive Astrocytes

Abstract Ischemic stroke is the most common cerebrovascular disease and the leading cause of permanent disability worldwide. Recent studies have shown that stroke development and prognosis are closely related to abnormal tryptophan metabolism. Here, significant downregulation of 3‐hydroxy‐kynurenami...

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Bibliographic Details
Main Authors: Jun‐Min Chen, Guang Shi, Lu‐Lu Yu, Wei Shan, Jing‐Yu Sun, An‐Chen Guo, Jian‐Ping Wu, Tie‐Shan Tang, Xiang‐Jian Zhang, Qun Wang
Format: Article
Language:English
Published: Wiley 2025-03-01
Series:Advanced Science
Subjects:
3‐hydroxy‐kynurenamine
AIM2 inflammasomes
ischemic stroke
reactive astrocytes
vascular remodeling
Online Access:https://doi.org/10.1002/advs.202412667
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