A BREAKTHROUGH VARICELLA: WILL A NEW VACCINATION SCHEDULE CHANGE THE SITUATION?

Varicella — is a common viral infection that can cause complications and adverse outcome not only in children at risk, but also in healthy children and adults. Socio-economic burden of disease due to both-direct health care, costs — to seek medical care and treatment,  and indirect — social. The int...

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Main Authors: E.A. Vishneva, L.S. Namazova-Baranova
Format: Article
Language:Russian
Published: Union of pediatricians of Russia 2011-12-01
Series:Педиатрическая фармакология
Online Access:https://www.pedpharma.ru/jour/article/view/1292
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author E.A. Vishneva
L.S. Namazova-Baranova
author_facet E.A. Vishneva
L.S. Namazova-Baranova
author_sort E.A. Vishneva
collection DOAJ
description Varicella — is a common viral infection that can cause complications and adverse outcome not only in children at risk, but also in healthy children and adults. Socio-economic burden of disease due to both-direct health care, costs — to seek medical care and treatment,  and indirect — social. The introduction of immunization after the development of live attenuated vaccine has shown impressive results provided high coverage of morbidity and mortality associated with chickenpox declined sharply. However, the development of infection in vaccinated patients — a breakthrough varicella may be related with the deterioration of post-vaccinal immunity with time,  and the primary tolerance and inability to induce an effective immune response. Despite the undeniable progress in the prevention of chicken pox since the early 2000s. the world’s a discussion about the need to move to the two-dose vaccination scheme in national immunization programs has been started. Key words: vaccination, children, chickenpox, varicella, breakout. (Pediatric pharmacology. — 2011; 8 (6): 18–22).
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spelling doaj-art-2753810a1d464e8497a6f2e097768f6f2025-08-20T03:19:41ZrusUnion of pediatricians of RussiaПедиатрическая фармакология1727-57762500-30892011-12-018618221287A BREAKTHROUGH VARICELLA: WILL A NEW VACCINATION SCHEDULE CHANGE THE SITUATION?E.A. Vishneva0L.S. Namazova-Baranova1Scientific Center for Children’s Health, RAMS, MoscowScientific Center for Children’s Health, RAMS, Moscow I.M. Sechenov First Moscow State Medical University N.I. Pirogov Russian National Research Medical University, MoscowVaricella — is a common viral infection that can cause complications and adverse outcome not only in children at risk, but also in healthy children and adults. Socio-economic burden of disease due to both-direct health care, costs — to seek medical care and treatment,  and indirect — social. The introduction of immunization after the development of live attenuated vaccine has shown impressive results provided high coverage of morbidity and mortality associated with chickenpox declined sharply. However, the development of infection in vaccinated patients — a breakthrough varicella may be related with the deterioration of post-vaccinal immunity with time,  and the primary tolerance and inability to induce an effective immune response. Despite the undeniable progress in the prevention of chicken pox since the early 2000s. the world’s a discussion about the need to move to the two-dose vaccination scheme in national immunization programs has been started. Key words: vaccination, children, chickenpox, varicella, breakout. (Pediatric pharmacology. — 2011; 8 (6): 18–22).https://www.pedpharma.ru/jour/article/view/1292
spellingShingle E.A. Vishneva
L.S. Namazova-Baranova
A BREAKTHROUGH VARICELLA: WILL A NEW VACCINATION SCHEDULE CHANGE THE SITUATION?
Педиатрическая фармакология
title A BREAKTHROUGH VARICELLA: WILL A NEW VACCINATION SCHEDULE CHANGE THE SITUATION?
title_full A BREAKTHROUGH VARICELLA: WILL A NEW VACCINATION SCHEDULE CHANGE THE SITUATION?
title_fullStr A BREAKTHROUGH VARICELLA: WILL A NEW VACCINATION SCHEDULE CHANGE THE SITUATION?
title_full_unstemmed A BREAKTHROUGH VARICELLA: WILL A NEW VACCINATION SCHEDULE CHANGE THE SITUATION?
title_short A BREAKTHROUGH VARICELLA: WILL A NEW VACCINATION SCHEDULE CHANGE THE SITUATION?
title_sort breakthrough varicella will a new vaccination schedule change the situation
url https://www.pedpharma.ru/jour/article/view/1292
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