Nanoporous copper as the hydrogen transfer catalyst for reduction of imines with silane/alcohol as the hydrogen source

The design and synthesis of sustainable nanocatalysts for novel and improved organic transformation are key tasks in organic chemistry. In this study, surface-oxidized nanoporous copper (np-Cu) was prepared using a dealloying method and oxygen desiccation treatment. This nanoporous catalyst promoted...

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Bibliographic Details
Main Authors: Mengyuan Li, Weina Guo, Liying Zhang, Bosen Yang, Zhiwen Li
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Results in Chemistry
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Online Access:http://www.sciencedirect.com/science/article/pii/S2211715625003169
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Summary:The design and synthesis of sustainable nanocatalysts for novel and improved organic transformation are key tasks in organic chemistry. In this study, surface-oxidized nanoporous copper (np-Cu) was prepared using a dealloying method and oxygen desiccation treatment. This nanoporous catalyst promoted the reductive amination of aldehydes, generating a series of N-alkylated secondary amines in high yields. Importantly, recycling experiments demonstrated that the np-Cu could be recovered and reused five times without any significant loss of activity. The obtained results indicate that np-Cu, which represents a tunable and economical nanoporous material, has the potential to be widely applied in other hydrogen transfer reactions.
ISSN:2211-7156