Beneficial Effects of Epigallocatechin Gallate in Preventing Skin Photoaging: A Review

Skin photoaging, primarily caused by ultraviolet (UV) radiation, leads to skin metabolic disorders, which have adverse psychological and physiological effects on individuals. However, traditional medications for repairing skin photoaging cause side effects. Natural bioactive compounds have been show...

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Main Authors: Jiaqiang Sun, Yuelu Jiang, Jing Fu, Linlin He, Xinmiao Guo, Hua Ye, Cuiyuan Yin, Hongbo Li, Heyuan Jiang
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Molecules
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Online Access:https://www.mdpi.com/1420-3049/29/22/5226
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author Jiaqiang Sun
Yuelu Jiang
Jing Fu
Linlin He
Xinmiao Guo
Hua Ye
Cuiyuan Yin
Hongbo Li
Heyuan Jiang
author_facet Jiaqiang Sun
Yuelu Jiang
Jing Fu
Linlin He
Xinmiao Guo
Hua Ye
Cuiyuan Yin
Hongbo Li
Heyuan Jiang
author_sort Jiaqiang Sun
collection DOAJ
description Skin photoaging, primarily caused by ultraviolet (UV) radiation, leads to skin metabolic disorders, which have adverse psychological and physiological effects on individuals. However, traditional medications for repairing skin photoaging cause side effects. Natural bioactive compounds have been shown to prevent and treat skin photoaging with fewer side effects. Epigallocatechin gallate (EGCG), the main substance in tea polyphenols, is a natural bioactive compound with a range of properties. This review summarizes the beneficial effects and mechanisms of EGCG, as well as the application forms of EGCG in repairing photoaged skin. Results indicated that EGCG has repair effects, including improving elasticity, enhancing moisturization, inhibiting damage, and reducing pigmentation of photoaged skin. It has also been demonstrated that EGCG delivery systems, modified EGCG, and combinations with other bioactive substances could be used for repairing photoaged skin due to its poor stability and low bioavailability. EGCG effectively repairs various types of skin damage caused by UV radiation while maintaining normal skin structure and function. It is, therefore, an effective candidate for repairing photoaged skin. These results could provide references for the development and application of EGCG products for the treatment of photoaged skin.
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spelling doaj-art-274746feb64c44f3be1fe58825b2ea692025-08-20T02:48:01ZengMDPI AGMolecules1420-30492024-11-012922522610.3390/molecules29225226Beneficial Effects of Epigallocatechin Gallate in Preventing Skin Photoaging: A ReviewJiaqiang Sun0Yuelu Jiang1Jing Fu2Linlin He3Xinmiao Guo4Hua Ye5Cuiyuan Yin6Hongbo Li7Heyuan Jiang8College of Biological Science and Engineering, Shaanxi University of Technology, Hanzhong 723001, ChinaCollege of Food Science and Engineering, Tianjin University of Science and Technology, Tianjin 300457, ChinaCollege of Biological Science and Engineering, Shaanxi University of Technology, Hanzhong 723001, ChinaCollege of Biological Science and Engineering, Shaanxi University of Technology, Hanzhong 723001, ChinaCollege of Biological Science and Engineering, Shaanxi University of Technology, Hanzhong 723001, ChinaCollege of Biological Science and Engineering, Shaanxi University of Technology, Hanzhong 723001, ChinaCollege of Biological Science and Engineering, Shaanxi University of Technology, Hanzhong 723001, ChinaCollege of Food Science and Engineering, Tianjin University of Science and Technology, Tianjin 300457, ChinaKey Laboratory of Special Economic Animal and Plant Biology and Genetic Breeding, Ministry of Agriculture and Rural Affairs, Tea Research Institute, Chinese Academy of Agricultural Sciences, Hangzhou 310008, ChinaSkin photoaging, primarily caused by ultraviolet (UV) radiation, leads to skin metabolic disorders, which have adverse psychological and physiological effects on individuals. However, traditional medications for repairing skin photoaging cause side effects. Natural bioactive compounds have been shown to prevent and treat skin photoaging with fewer side effects. Epigallocatechin gallate (EGCG), the main substance in tea polyphenols, is a natural bioactive compound with a range of properties. This review summarizes the beneficial effects and mechanisms of EGCG, as well as the application forms of EGCG in repairing photoaged skin. Results indicated that EGCG has repair effects, including improving elasticity, enhancing moisturization, inhibiting damage, and reducing pigmentation of photoaged skin. It has also been demonstrated that EGCG delivery systems, modified EGCG, and combinations with other bioactive substances could be used for repairing photoaged skin due to its poor stability and low bioavailability. EGCG effectively repairs various types of skin damage caused by UV radiation while maintaining normal skin structure and function. It is, therefore, an effective candidate for repairing photoaged skin. These results could provide references for the development and application of EGCG products for the treatment of photoaged skin.https://www.mdpi.com/1420-3049/29/22/5226ultraviolet (UV)skin photoagingepigallocatechin gallate (EGCG)beneficial effects
spellingShingle Jiaqiang Sun
Yuelu Jiang
Jing Fu
Linlin He
Xinmiao Guo
Hua Ye
Cuiyuan Yin
Hongbo Li
Heyuan Jiang
Beneficial Effects of Epigallocatechin Gallate in Preventing Skin Photoaging: A Review
Molecules
ultraviolet (UV)
skin photoaging
epigallocatechin gallate (EGCG)
beneficial effects
title Beneficial Effects of Epigallocatechin Gallate in Preventing Skin Photoaging: A Review
title_full Beneficial Effects of Epigallocatechin Gallate in Preventing Skin Photoaging: A Review
title_fullStr Beneficial Effects of Epigallocatechin Gallate in Preventing Skin Photoaging: A Review
title_full_unstemmed Beneficial Effects of Epigallocatechin Gallate in Preventing Skin Photoaging: A Review
title_short Beneficial Effects of Epigallocatechin Gallate in Preventing Skin Photoaging: A Review
title_sort beneficial effects of epigallocatechin gallate in preventing skin photoaging a review
topic ultraviolet (UV)
skin photoaging
epigallocatechin gallate (EGCG)
beneficial effects
url https://www.mdpi.com/1420-3049/29/22/5226
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