Rapid enrichment and SERS detection of fenitrothion and methyl parathion in vegetable and fruit juices using a dual-functionalized microneedle

Fenitrothion and methyl parathion residues pose significant public health risks. Efficiently extracting and real-time detecting pesticide residues in complex matrices remains challenging. This study presents an ultrafast enrichment and SERS detection approach, achieving rapid analysis of fenitrothio...

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Main Authors: Mengping Zhang, Hui Pan, Yafen Zeng, Xiao Meng, Wenwen Chen, Meng Jin, Hua Shao, Haiyan Wei, Cuijuan Wang
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Current Research in Food Science
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Online Access:http://www.sciencedirect.com/science/article/pii/S2665927125001376
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Summary:Fenitrothion and methyl parathion residues pose significant public health risks. Efficiently extracting and real-time detecting pesticide residues in complex matrices remains challenging. This study presents an ultrafast enrichment and SERS detection approach, achieving rapid analysis of fenitrothion and methyl parathion in vegetable and fruit juices using a dual-functionalized microneedle. A point-of-use SERS-active microneedle was developed with rough silver covered with an Au layer for ultrafast electro-enhanced microextraction (EEM) and sensitive SERS response toward real-time monitoring. Applying a negative electric potential to the dual-functionalized microneedle, pesticide enrichment was accelerated, achieving a tenfold increase in efficiency over traditional static strategy. The EEM-SERS process can be completed in 5 min, with strong correlations noted between SERS intensity and pesticide concentrations (r2 = 0.940–0.976). The detection limits for fenitrothion and methyl parathion were 1.08–1.88 ppb in celery and orange juice, demonstrating the method's effectiveness for quick in situ pesticide residue detection.
ISSN:2665-9271