Complexin regulation of synaptic vesicle release: mechanisms in the central nervous system and specialized retinal ribbon synapses

Complexin regulation of synaptic vesicle release: mechanisms in the central nervous system and specialized retinal ribbon synapses

Abstract Synaptic ribbons, recognized for their pivotal role in conveying sensory signals in the visual pathway, are intricate assemblages of presynaptic proteins. Complexin (CPX) regulates synaptic vesicle fusion and neurotransmitter release by modulating the assembly of the soluble NSF attachment...

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Bibliographic Details
Main Authors: Yun-Zhi Li, Yu Wang, Qing Jiao, Jing Chi, Yang Liang, Bin Fan, Guang-Yu Li
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Cell Communication and Signaling
Subjects:
Complexin
Ribbon synapse
Photoreceptor synapse
SNARE complex
Retina
Central nervous system
Online Access:https://doi.org/10.1186/s12964-024-01942-x
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