Bioactive toothpastes in dentin hypersensitivity treatment: A systematic review

Purpose: The use of bioactive materials is a recent proposal in the treatment of dentin hypersensitivity (DH) due to the ability to stimulate the neoformation of a barrier on dentin surface. Questions have arisen about the effectiveness of the materials to reduce DH when compared to the control grou...

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Main Authors: Samantha Ariadne Alves de Freitas, Neurinéia Margarida Alves de Oliveira, Juliana Larocca de Geus, Soraia de Fátima Carvalho Souza, Adriana de Fátima Vasconcelos Pereira, José Bauer
Format: Article
Language:English
Published: Springer 2021-11-01
Series:Saudi Dental Journal
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Online Access:http://www.sciencedirect.com/science/article/pii/S1013905221000481
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author Samantha Ariadne Alves de Freitas
Neurinéia Margarida Alves de Oliveira
Juliana Larocca de Geus
Soraia de Fátima Carvalho Souza
Adriana de Fátima Vasconcelos Pereira
José Bauer
author_facet Samantha Ariadne Alves de Freitas
Neurinéia Margarida Alves de Oliveira
Juliana Larocca de Geus
Soraia de Fátima Carvalho Souza
Adriana de Fátima Vasconcelos Pereira
José Bauer
author_sort Samantha Ariadne Alves de Freitas
collection DOAJ
description Purpose: The use of bioactive materials is a recent proposal in the treatment of dentin hypersensitivity (DH) due to the ability to stimulate the neoformation of a barrier on dentin surface. Questions have arisen about the effectiveness of the materials to reduce DH when compared to the control groups (placebo or non-bioactive substance). Thus, the aim of this systematic review was to evaluate the randomized controlled trials in adult patients for DH treatment with a dentifrice containing bioactive glass, applied either at-home or in-office. Methods: The study was registered in PROSPERO and followed PRISMA guidelines. Searches were carried out in four databases (Pubmed/Medline, CENTRAL, Wbb of Science, LILACS) spanning from February 2020 to March 2020, with no language or publication date restrictions. A supplementary hand-search was performed by checking the list of references. The so-called gray literature of the national and international databases for theses and dissertations, as well as unfinished, in progress and unpublished studies were also searched. Results: After reading the titles and abstracts, articles that were duplicated (74 records) or unrelated to the systematic review (76 records) were excluded. Fifteen studies were evaluated considering seven at low risk of bias, four at high risk and four at moderate risk. Conclusion: The bioactive compounds at low concentrations (2.5–7.5%) can be used as treatment of DH both at-home and in-office.
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spelling doaj-art-2735e9f3bdf24c6dbccf8d12192a40652025-08-20T02:56:34ZengSpringerSaudi Dental Journal1013-90522021-11-0133739540310.1016/j.sdentj.2021.04.004Bioactive toothpastes in dentin hypersensitivity treatment: A systematic reviewSamantha Ariadne Alves de Freitas0Neurinéia Margarida Alves de Oliveira1Juliana Larocca de Geus2Soraia de Fátima Carvalho Souza3Adriana de Fátima Vasconcelos Pereira4José Bauer5School of Dentistry, Federal University of Maranhão (UFMA), São Luís, Maranhão, BrazilSchool of Dentistry, Federal University of Maranhão (UFMA), São Luís, Maranhão, BrazilSchool of Dentistry, Paulo Picanço Faculty, Fortaleza, Ceará, BrazilSchool of Dentistry, Federal University of Maranhão (UFMA), São Luís, Maranhão, BrazilSchool of Dentistry, Federal University of Maranhão (UFMA), São Luís, Maranhão, BrazilSchool of Dentistry, Federal University of Maranhão (UFMA), São Luís, Maranhão, Brazil; Corresponding author at: Discipline of Dental Materials, School of Dentistry, Federal University of Maranhão (UFMA) - Av. Portugueses, 1966 – Bacanga, Sao Luis, MA 65085-580, Brazil.Purpose: The use of bioactive materials is a recent proposal in the treatment of dentin hypersensitivity (DH) due to the ability to stimulate the neoformation of a barrier on dentin surface. Questions have arisen about the effectiveness of the materials to reduce DH when compared to the control groups (placebo or non-bioactive substance). Thus, the aim of this systematic review was to evaluate the randomized controlled trials in adult patients for DH treatment with a dentifrice containing bioactive glass, applied either at-home or in-office. Methods: The study was registered in PROSPERO and followed PRISMA guidelines. Searches were carried out in four databases (Pubmed/Medline, CENTRAL, Wbb of Science, LILACS) spanning from February 2020 to March 2020, with no language or publication date restrictions. A supplementary hand-search was performed by checking the list of references. The so-called gray literature of the national and international databases for theses and dissertations, as well as unfinished, in progress and unpublished studies were also searched. Results: After reading the titles and abstracts, articles that were duplicated (74 records) or unrelated to the systematic review (76 records) were excluded. Fifteen studies were evaluated considering seven at low risk of bias, four at high risk and four at moderate risk. Conclusion: The bioactive compounds at low concentrations (2.5–7.5%) can be used as treatment of DH both at-home and in-office.http://www.sciencedirect.com/science/article/pii/S1013905221000481Dentin sensitivityClinical trialDentin desensitizing agentsBioactive glass
spellingShingle Samantha Ariadne Alves de Freitas
Neurinéia Margarida Alves de Oliveira
Juliana Larocca de Geus
Soraia de Fátima Carvalho Souza
Adriana de Fátima Vasconcelos Pereira
José Bauer
Bioactive toothpastes in dentin hypersensitivity treatment: A systematic review
Saudi Dental Journal
Dentin sensitivity
Clinical trial
Dentin desensitizing agents
Bioactive glass
title Bioactive toothpastes in dentin hypersensitivity treatment: A systematic review
title_full Bioactive toothpastes in dentin hypersensitivity treatment: A systematic review
title_fullStr Bioactive toothpastes in dentin hypersensitivity treatment: A systematic review
title_full_unstemmed Bioactive toothpastes in dentin hypersensitivity treatment: A systematic review
title_short Bioactive toothpastes in dentin hypersensitivity treatment: A systematic review
title_sort bioactive toothpastes in dentin hypersensitivity treatment a systematic review
topic Dentin sensitivity
Clinical trial
Dentin desensitizing agents
Bioactive glass
url http://www.sciencedirect.com/science/article/pii/S1013905221000481
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