Field efficacy of Vectobac GR as a mosquito larvicide for the control of anopheline and culicine mosquitoes in natural habitats in Benin, West Africa.
<h4>Introduction</h4>The efficacy of Vectobac GR (potency 200 ITU/mg), a new formulation of bacterial larvicide Bacillus thuringiensis var. israelensis Strain AM65-52, was evaluated against Anopheles gambiae and Culex quinquefasciatus in simulated field and natural habitats in Benin.<...
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Public Library of Science (PLoS)
2014-01-01
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| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0087934 |
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| author | Armel Djènontin Cédric Pennetier Barnabas Zogo Koffi Bhonna Soukou Marina Ole-Sangba Martin Akogbéto Fabrice Chandre Rajpal Yadav Vincent Corbel |
| author_facet | Armel Djènontin Cédric Pennetier Barnabas Zogo Koffi Bhonna Soukou Marina Ole-Sangba Martin Akogbéto Fabrice Chandre Rajpal Yadav Vincent Corbel |
| author_sort | Armel Djènontin |
| collection | DOAJ |
| description | <h4>Introduction</h4>The efficacy of Vectobac GR (potency 200 ITU/mg), a new formulation of bacterial larvicide Bacillus thuringiensis var. israelensis Strain AM65-52, was evaluated against Anopheles gambiae and Culex quinquefasciatus in simulated field and natural habitats in Benin.<h4>Methods</h4>In simulated field conditions, Vectobac GR formulation was tested at 3 dosages (0.6, 0.9, 1.2 g granules/m² against An. gambiae and 1, 1.5, 2 g granules/m² against Cx. quinquefasciatus) according to manufacturer's product label recommendations. The dosage giving optimum efficacy under simulated field conditions were evaluated in the field. The efficacy of Vectobac GR in terms of emergence inhibition in simulated field conditions and of reduction of larval and pupal densities in rice fields and urban cesspits was measured following WHO guidelines for testing and evaluation of mosquito larvicides.<h4>Results</h4>Vectobac GR caused emergence inhibition of ≥80% until 21 [20]-[22] days for An. gambiae at 1.2 g/m² dose and 28 [27-29] days for Cx. quinquefasciatus at 2 g/m² in simulated field habitats. The efficacy of Vectobac GR in natural habitats was for 2 to 3 days against larvae and up to 10 days against pupae.<h4>Conclusions</h4>Treatment with Vectobac GR caused complete control of immature mosquito within 2-3 days but did not show prolonged residual action. Larviciding can be an option for malaria and filariasis vector control particularly in managing pyrethroid-resistance in African malaria vectors. Since use of larvicides among several African countries is being emphasized through Economic Community of West Africa States, their epidemiological impact should be carefully investigated. |
| format | Article |
| id | doaj-art-272f495487b6412ca4844378cd6d0ea1 |
| institution | OA Journals |
| issn | 1932-6203 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Public Library of Science (PLoS) |
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| series | PLoS ONE |
| spelling | doaj-art-272f495487b6412ca4844378cd6d0ea12025-08-20T02:34:14ZengPublic Library of Science (PLoS)PLoS ONE1932-62032014-01-0192e8793410.1371/journal.pone.0087934Field efficacy of Vectobac GR as a mosquito larvicide for the control of anopheline and culicine mosquitoes in natural habitats in Benin, West Africa.Armel DjènontinCédric PennetierBarnabas ZogoKoffi Bhonna SoukouMarina Ole-SangbaMartin AkogbétoFabrice ChandreRajpal YadavVincent Corbel<h4>Introduction</h4>The efficacy of Vectobac GR (potency 200 ITU/mg), a new formulation of bacterial larvicide Bacillus thuringiensis var. israelensis Strain AM65-52, was evaluated against Anopheles gambiae and Culex quinquefasciatus in simulated field and natural habitats in Benin.<h4>Methods</h4>In simulated field conditions, Vectobac GR formulation was tested at 3 dosages (0.6, 0.9, 1.2 g granules/m² against An. gambiae and 1, 1.5, 2 g granules/m² against Cx. quinquefasciatus) according to manufacturer's product label recommendations. The dosage giving optimum efficacy under simulated field conditions were evaluated in the field. The efficacy of Vectobac GR in terms of emergence inhibition in simulated field conditions and of reduction of larval and pupal densities in rice fields and urban cesspits was measured following WHO guidelines for testing and evaluation of mosquito larvicides.<h4>Results</h4>Vectobac GR caused emergence inhibition of ≥80% until 21 [20]-[22] days for An. gambiae at 1.2 g/m² dose and 28 [27-29] days for Cx. quinquefasciatus at 2 g/m² in simulated field habitats. The efficacy of Vectobac GR in natural habitats was for 2 to 3 days against larvae and up to 10 days against pupae.<h4>Conclusions</h4>Treatment with Vectobac GR caused complete control of immature mosquito within 2-3 days but did not show prolonged residual action. Larviciding can be an option for malaria and filariasis vector control particularly in managing pyrethroid-resistance in African malaria vectors. Since use of larvicides among several African countries is being emphasized through Economic Community of West Africa States, their epidemiological impact should be carefully investigated.https://doi.org/10.1371/journal.pone.0087934 |
| spellingShingle | Armel Djènontin Cédric Pennetier Barnabas Zogo Koffi Bhonna Soukou Marina Ole-Sangba Martin Akogbéto Fabrice Chandre Rajpal Yadav Vincent Corbel Field efficacy of Vectobac GR as a mosquito larvicide for the control of anopheline and culicine mosquitoes in natural habitats in Benin, West Africa. PLoS ONE |
| title | Field efficacy of Vectobac GR as a mosquito larvicide for the control of anopheline and culicine mosquitoes in natural habitats in Benin, West Africa. |
| title_full | Field efficacy of Vectobac GR as a mosquito larvicide for the control of anopheline and culicine mosquitoes in natural habitats in Benin, West Africa. |
| title_fullStr | Field efficacy of Vectobac GR as a mosquito larvicide for the control of anopheline and culicine mosquitoes in natural habitats in Benin, West Africa. |
| title_full_unstemmed | Field efficacy of Vectobac GR as a mosquito larvicide for the control of anopheline and culicine mosquitoes in natural habitats in Benin, West Africa. |
| title_short | Field efficacy of Vectobac GR as a mosquito larvicide for the control of anopheline and culicine mosquitoes in natural habitats in Benin, West Africa. |
| title_sort | field efficacy of vectobac gr as a mosquito larvicide for the control of anopheline and culicine mosquitoes in natural habitats in benin west africa |
| url | https://doi.org/10.1371/journal.pone.0087934 |
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