Case report: Basal cell carcinoma arising within the nevus sebaceous: report of 4 cases and literature review
Nevus sebaceous (NS) is a congenital hamartoma characterized by the presence of skin structures, including the epidermis, sebaceous glands, and hair follicles. NS predominantly occurs on the scalp and has the potential to give rise to secondary tumors, with a small proportion being malignant; the mo...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-01-01
|
| Series: | Frontiers in Oncology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fonc.2024.1478747/full |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1841556848077963264 |
|---|---|
| author | Tianbing Lei Yonghong Lu Yanyan Feng Yao Ni |
| author_facet | Tianbing Lei Yonghong Lu Yanyan Feng Yao Ni |
| author_sort | Tianbing Lei |
| collection | DOAJ |
| description | Nevus sebaceous (NS) is a congenital hamartoma characterized by the presence of skin structures, including the epidermis, sebaceous glands, and hair follicles. NS predominantly occurs on the scalp and has the potential to give rise to secondary tumors, with a small proportion being malignant; the most frequently observed malignant tumor associated with NS is basal cell carcinoma. In this report, we retrospectively present four cases of sebaceous nevus on the scalp complicated by basal cell carcinoma. The pathological diagnoses were unequivocal in all four patients, who exhibited typical clinical manifestations, with all cases localized to the left parietotemporal region of the scalp. The etiology of NS may be linked to genetic mutations or ultraviolet exposure. Treatment options vary, with surgical resection likely being the most common method of eradication. |
| format | Article |
| id | doaj-art-272067b9fc814975b3ab093c1fd394f5 |
| institution | Kabale University |
| issn | 2234-943X |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Oncology |
| spelling | doaj-art-272067b9fc814975b3ab093c1fd394f52025-01-07T05:24:01ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2025-01-011410.3389/fonc.2024.14787471478747Case report: Basal cell carcinoma arising within the nevus sebaceous: report of 4 cases and literature reviewTianbing LeiYonghong LuYanyan FengYao NiNevus sebaceous (NS) is a congenital hamartoma characterized by the presence of skin structures, including the epidermis, sebaceous glands, and hair follicles. NS predominantly occurs on the scalp and has the potential to give rise to secondary tumors, with a small proportion being malignant; the most frequently observed malignant tumor associated with NS is basal cell carcinoma. In this report, we retrospectively present four cases of sebaceous nevus on the scalp complicated by basal cell carcinoma. The pathological diagnoses were unequivocal in all four patients, who exhibited typical clinical manifestations, with all cases localized to the left parietotemporal region of the scalp. The etiology of NS may be linked to genetic mutations or ultraviolet exposure. Treatment options vary, with surgical resection likely being the most common method of eradication.https://www.frontiersin.org/articles/10.3389/fonc.2024.1478747/fullnevus sebaceousbasal cell carcinomamalignant degenerationgeneultraviolet |
| spellingShingle | Tianbing Lei Yonghong Lu Yanyan Feng Yao Ni Case report: Basal cell carcinoma arising within the nevus sebaceous: report of 4 cases and literature review Frontiers in Oncology nevus sebaceous basal cell carcinoma malignant degeneration gene ultraviolet |
| title | Case report: Basal cell carcinoma arising within the nevus sebaceous: report of 4 cases and literature review |
| title_full | Case report: Basal cell carcinoma arising within the nevus sebaceous: report of 4 cases and literature review |
| title_fullStr | Case report: Basal cell carcinoma arising within the nevus sebaceous: report of 4 cases and literature review |
| title_full_unstemmed | Case report: Basal cell carcinoma arising within the nevus sebaceous: report of 4 cases and literature review |
| title_short | Case report: Basal cell carcinoma arising within the nevus sebaceous: report of 4 cases and literature review |
| title_sort | case report basal cell carcinoma arising within the nevus sebaceous report of 4 cases and literature review |
| topic | nevus sebaceous basal cell carcinoma malignant degeneration gene ultraviolet |
| url | https://www.frontiersin.org/articles/10.3389/fonc.2024.1478747/full |
| work_keys_str_mv | AT tianbinglei casereportbasalcellcarcinomaarisingwithinthenevussebaceousreportof4casesandliteraturereview AT yonghonglu casereportbasalcellcarcinomaarisingwithinthenevussebaceousreportof4casesandliteraturereview AT yanyanfeng casereportbasalcellcarcinomaarisingwithinthenevussebaceousreportof4casesandliteraturereview AT yaoni casereportbasalcellcarcinomaarisingwithinthenevussebaceousreportof4casesandliteraturereview |