Effects of SARS-CoV-2 Infection on Menstruation in Vaccinated Women: A Monocentric Retrospective Study
Background: Many studies have reported irregular menstruation in women of childbearing age after vaccination or infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, no studies have discussed the changes in menstrual patterns after reinfection with SARS-CoV-2 after va...
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| Format: | Article |
| Language: | English |
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IMR Press
2024-07-01
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| Series: | Clinical and Experimental Obstetrics & Gynecology |
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| Online Access: | https://www.imrpress.com/journal/CEOG/51/7/10.31083/j.ceog5107168 |
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| author | Ruide Su Jiahui Lin Huanxin Duan Wenrong Wang Jian An |
| author_facet | Ruide Su Jiahui Lin Huanxin Duan Wenrong Wang Jian An |
| author_sort | Ruide Su |
| collection | DOAJ |
| description | Background: Many studies have reported irregular menstruation in women of childbearing age after vaccination or infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, no studies have discussed the changes in menstrual patterns after reinfection with SARS-CoV-2 after vaccination. This study aimed to evaluate the effect of SARS-CoV-2 infection on menstruation in vaccinated and unvaccinated women of reproductive age. Methods: This retrospective study analysed the menstrual data of 241 women of childbearing age. Between December 8th, 2022 and February 11th, 2023, 201 participants were diagnosed with SARS-CoV-2 infection (observation group), while 40 remained uninfected (control group). The Chi-square test and Fisher’s exact test were used to assess menstrual irregularities among the participants. Logistic regression analysis was performed to determine the factors influencing menstrual patterns. Results: Among the 241 women who completed the survey, approximately one-third experienced changes in their menstrual patterns, including a shortened cycle (30.3%), a prolonged duration (13%), a decreased volume (24.9%), and increased dysmenorrhea (9.9%). Over half of the infected women did not experience any changes in their menstrual pattern. Only changes in the menstrual volume were statistically significant (p = 0.003). Logistic regression revealed that vaccination may be a protective factor against changes in the menstrual cycle (p = 0.036, odds ratio (OR) = 0.703, 95% confidence interval (95% CI): 0.506–0.977) and volume (p = 0.032, OR = 0.700, 95% CI: 0.505–0.969) after SARS-CoV-2 infection. Conclusions: SARS-CoV-2 infection did not appear to affect menstruation in vaccinated women. There were no significant changes in menstrual patterns except for menstrual cycle in women infected with SARS-CoV-2 after coronavirus disease 2019 (COVID-19) vaccination. In addition, vaccination seems to be a protective factor against changes in the menstrual cycle and volume after SARS-CoV-2 infection. |
| format | Article |
| id | doaj-art-271d21b0127d40a290be4797d239da96 |
| institution | DOAJ |
| issn | 0390-6663 |
| language | English |
| publishDate | 2024-07-01 |
| publisher | IMR Press |
| record_format | Article |
| series | Clinical and Experimental Obstetrics & Gynecology |
| spelling | doaj-art-271d21b0127d40a290be4797d239da962025-08-20T03:17:55ZengIMR PressClinical and Experimental Obstetrics & Gynecology0390-66632024-07-0151716810.31083/j.ceog5107168S0390-6663(24)02415-1Effects of SARS-CoV-2 Infection on Menstruation in Vaccinated Women: A Monocentric Retrospective StudyRuide Su0Jiahui Lin1Huanxin Duan2Wenrong Wang3Jian An4Department of Aristogenesis Clinic (Birth Control), Women and Children’s Hospital, School of Medicine, Xiamen University, 361000 Xiamen, Fujian, ChinaDepartment of Aristogenesis Clinic (Birth Control), Women and Children’s Hospital, School of Medicine, Xiamen University, 361000 Xiamen, Fujian, ChinaDepartment of Aristogenesis Clinic (Birth Control), Women and Children’s Hospital, School of Medicine, Xiamen University, 361000 Xiamen, Fujian, ChinaDepartment of Aristogenesis Clinic (Birth Control), Women and Children’s Hospital, School of Medicine, Xiamen University, 361000 Xiamen, Fujian, ChinaDepartment of Gynecology, Women and Children’s Hospital, School of Medicine, Xiamen University, 361000 Xiamen, Fujian, ChinaBackground: Many studies have reported irregular menstruation in women of childbearing age after vaccination or infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, no studies have discussed the changes in menstrual patterns after reinfection with SARS-CoV-2 after vaccination. This study aimed to evaluate the effect of SARS-CoV-2 infection on menstruation in vaccinated and unvaccinated women of reproductive age. Methods: This retrospective study analysed the menstrual data of 241 women of childbearing age. Between December 8th, 2022 and February 11th, 2023, 201 participants were diagnosed with SARS-CoV-2 infection (observation group), while 40 remained uninfected (control group). The Chi-square test and Fisher’s exact test were used to assess menstrual irregularities among the participants. Logistic regression analysis was performed to determine the factors influencing menstrual patterns. Results: Among the 241 women who completed the survey, approximately one-third experienced changes in their menstrual patterns, including a shortened cycle (30.3%), a prolonged duration (13%), a decreased volume (24.9%), and increased dysmenorrhea (9.9%). Over half of the infected women did not experience any changes in their menstrual pattern. Only changes in the menstrual volume were statistically significant (p = 0.003). Logistic regression revealed that vaccination may be a protective factor against changes in the menstrual cycle (p = 0.036, odds ratio (OR) = 0.703, 95% confidence interval (95% CI): 0.506–0.977) and volume (p = 0.032, OR = 0.700, 95% CI: 0.505–0.969) after SARS-CoV-2 infection. Conclusions: SARS-CoV-2 infection did not appear to affect menstruation in vaccinated women. There were no significant changes in menstrual patterns except for menstrual cycle in women infected with SARS-CoV-2 after coronavirus disease 2019 (COVID-19) vaccination. In addition, vaccination seems to be a protective factor against changes in the menstrual cycle and volume after SARS-CoV-2 infection.https://www.imrpress.com/journal/CEOG/51/7/10.31083/j.ceog5107168covid-19sars-cov-2menstruationvaccines |
| spellingShingle | Ruide Su Jiahui Lin Huanxin Duan Wenrong Wang Jian An Effects of SARS-CoV-2 Infection on Menstruation in Vaccinated Women: A Monocentric Retrospective Study Clinical and Experimental Obstetrics & Gynecology covid-19 sars-cov-2 menstruation vaccines |
| title | Effects of SARS-CoV-2 Infection on Menstruation in Vaccinated Women: A Monocentric Retrospective Study |
| title_full | Effects of SARS-CoV-2 Infection on Menstruation in Vaccinated Women: A Monocentric Retrospective Study |
| title_fullStr | Effects of SARS-CoV-2 Infection on Menstruation in Vaccinated Women: A Monocentric Retrospective Study |
| title_full_unstemmed | Effects of SARS-CoV-2 Infection on Menstruation in Vaccinated Women: A Monocentric Retrospective Study |
| title_short | Effects of SARS-CoV-2 Infection on Menstruation in Vaccinated Women: A Monocentric Retrospective Study |
| title_sort | effects of sars cov 2 infection on menstruation in vaccinated women a monocentric retrospective study |
| topic | covid-19 sars-cov-2 menstruation vaccines |
| url | https://www.imrpress.com/journal/CEOG/51/7/10.31083/j.ceog5107168 |
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