Mucosal Advancement Flap for Fistula-in-ano: A Single-Institution Experience

Background and Objective: Mucosal advancement flap (MAF) is a well-described definitive treatment for complex fistula-in-ano, with high healing rates ranging from 37 to 87% for cryptoglandular fistula, but with mild incontinence rates of up to 35%. There is a paucity of Australian data to support th...

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Main Authors: Yui Kaneko, David Lam, James Keck, Rodney Woods
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2018-01-01
Series:World Journal of Colorectal Surgery
Subjects:
Online Access:https://journals.lww.com/10.4103/1941-8213.240254
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author Yui Kaneko
David Lam
James Keck
Rodney Woods
author_facet Yui Kaneko
David Lam
James Keck
Rodney Woods
author_sort Yui Kaneko
collection DOAJ
description Background and Objective: Mucosal advancement flap (MAF) is a well-described definitive treatment for complex fistula-in-ano, with high healing rates ranging from 37 to 87% for cryptoglandular fistula, but with mild incontinence rates of up to 35%. There is a paucity of Australian data to support the efficacy and complication rates of MAF, nor predictive factors for success. Patients and Methods: This was a retrospective study, with ethical approval granted by St. Vincent's Hospital Melbourne (SVHM) Quality and Risk Unit. Patients who underwent MAF at SVHM and St Vincent's Private Hospital Fitzroy from 2011 to 2015 were included in the study; all data were collected from patient medical records. Results: A total of 65 patients were treated with MAF during the study period. Fistula etiology was cryptoglandular in 82%, anovaginal in 11%, and perianal Crohn's disease in 7% of patients. Overall success rates for MAF were 66% for cryptoglandular fistula, 14% for anovaginal fistula, and 40% for Crohn's fistula. Excluding anovaginal fistulae, the success rate of MAF was 74% for males and 57% for females. MAF performed for an anterior internal opening was associated with a success rate of 65% versus 56% for a posterior internal opening. Postoperative fecal incontinence rate was 6%. Five of the patients with failed MAF underwent a second sphincter-preserving procedure; none of these were successful. Conclusion: This study supports the use of MAF for the treatment of complex fistula-in-ano, with a success rate compatible with existing literature and a low incontinence rate.
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spelling doaj-art-271b109f8cb74d19b48aec59bfa698e92025-08-20T02:18:46ZengWolters Kluwer Medknow PublicationsWorld Journal of Colorectal Surgery1941-82132018-01-0171121510.4103/1941-8213.240254Mucosal Advancement Flap for Fistula-in-ano: A Single-Institution ExperienceYui KanekoDavid LamJames KeckRodney WoodsBackground and Objective: Mucosal advancement flap (MAF) is a well-described definitive treatment for complex fistula-in-ano, with high healing rates ranging from 37 to 87% for cryptoglandular fistula, but with mild incontinence rates of up to 35%. There is a paucity of Australian data to support the efficacy and complication rates of MAF, nor predictive factors for success. Patients and Methods: This was a retrospective study, with ethical approval granted by St. Vincent's Hospital Melbourne (SVHM) Quality and Risk Unit. Patients who underwent MAF at SVHM and St Vincent's Private Hospital Fitzroy from 2011 to 2015 were included in the study; all data were collected from patient medical records. Results: A total of 65 patients were treated with MAF during the study period. Fistula etiology was cryptoglandular in 82%, anovaginal in 11%, and perianal Crohn's disease in 7% of patients. Overall success rates for MAF were 66% for cryptoglandular fistula, 14% for anovaginal fistula, and 40% for Crohn's fistula. Excluding anovaginal fistulae, the success rate of MAF was 74% for males and 57% for females. MAF performed for an anterior internal opening was associated with a success rate of 65% versus 56% for a posterior internal opening. Postoperative fecal incontinence rate was 6%. Five of the patients with failed MAF underwent a second sphincter-preserving procedure; none of these were successful. Conclusion: This study supports the use of MAF for the treatment of complex fistula-in-ano, with a success rate compatible with existing literature and a low incontinence rate.https://journals.lww.com/10.4103/1941-8213.240254complex anal fistulafistula-in-anomucosal advancement flap
spellingShingle Yui Kaneko
David Lam
James Keck
Rodney Woods
Mucosal Advancement Flap for Fistula-in-ano: A Single-Institution Experience
World Journal of Colorectal Surgery
complex anal fistula
fistula-in-ano
mucosal advancement flap
title Mucosal Advancement Flap for Fistula-in-ano: A Single-Institution Experience
title_full Mucosal Advancement Flap for Fistula-in-ano: A Single-Institution Experience
title_fullStr Mucosal Advancement Flap for Fistula-in-ano: A Single-Institution Experience
title_full_unstemmed Mucosal Advancement Flap for Fistula-in-ano: A Single-Institution Experience
title_short Mucosal Advancement Flap for Fistula-in-ano: A Single-Institution Experience
title_sort mucosal advancement flap for fistula in ano a single institution experience
topic complex anal fistula
fistula-in-ano
mucosal advancement flap
url https://journals.lww.com/10.4103/1941-8213.240254
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AT davidlam mucosaladvancementflapforfistulainanoasingleinstitutionexperience
AT jameskeck mucosaladvancementflapforfistulainanoasingleinstitutionexperience
AT rodneywoods mucosaladvancementflapforfistulainanoasingleinstitutionexperience