Intra-Articular Polyacrylamide Hydrogel Injections Are Not Innocent

Osteoarthritis is a chronic disorder characterized by joint cartilage degeneration with concomitant changes in the synovium and subchondral bone metabolism. Many conservative treatment modalities, one of which is intra-articular injections, have been described for the treatment of this disorder. Tra...

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Main Authors: Murat Tonbul, Mujdat Adas, Taner Bekmezci, Ahmet Duran Kara
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Case Reports in Orthopedics
Online Access:http://dx.doi.org/10.1155/2014/150709
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author Murat Tonbul
Mujdat Adas
Taner Bekmezci
Ahmet Duran Kara
author_facet Murat Tonbul
Mujdat Adas
Taner Bekmezci
Ahmet Duran Kara
author_sort Murat Tonbul
collection DOAJ
description Osteoarthritis is a chronic disorder characterized by joint cartilage degeneration with concomitant changes in the synovium and subchondral bone metabolism. Many conservative treatment modalities, one of which is intra-articular injections, have been described for the treatment of this disorder. Traditionally, hyaluranic acid and corticosteroids are the agents that have been used for this purpose. Recently, polyacrylamide hydrogels are being used widely. Biocompatibility, nonbioabsorbability, and anti-infectious effect obtained by silver addition made polyacrylamide hydrogels more popular. In this paper, we present a case and the method of our management, in whom host tissue reaction (foreign body granuloma, edema, inflammation, and redness induration) has been observed, as the first and unique adverse effect reported in the literature.
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id doaj-art-26ee80c7c70c4cb685d02266b9d6c340
institution Kabale University
issn 2090-6749
2090-6757
language English
publishDate 2014-01-01
publisher Wiley
record_format Article
series Case Reports in Orthopedics
spelling doaj-art-26ee80c7c70c4cb685d02266b9d6c3402025-02-03T05:58:16ZengWileyCase Reports in Orthopedics2090-67492090-67572014-01-01201410.1155/2014/150709150709Intra-Articular Polyacrylamide Hydrogel Injections Are Not InnocentMurat Tonbul0Mujdat Adas1Taner Bekmezci2Ahmet Duran Kara3Orthopedics and Traumatology Department, Private Reyap Hospital, Çorlu, 59860 Tekirdağ, TurkeyOrthopedics and Traumatology Department, Istanbul Okmeydani Hospital for Research and Education, TurkeyOrthopedics and Traumatology, Istanbul Liv Hospital, TurkeyOrthopedics and Traumatology Department, Private Reyap Hospital, Çorlu, 59860 Tekirdağ, TurkeyOsteoarthritis is a chronic disorder characterized by joint cartilage degeneration with concomitant changes in the synovium and subchondral bone metabolism. Many conservative treatment modalities, one of which is intra-articular injections, have been described for the treatment of this disorder. Traditionally, hyaluranic acid and corticosteroids are the agents that have been used for this purpose. Recently, polyacrylamide hydrogels are being used widely. Biocompatibility, nonbioabsorbability, and anti-infectious effect obtained by silver addition made polyacrylamide hydrogels more popular. In this paper, we present a case and the method of our management, in whom host tissue reaction (foreign body granuloma, edema, inflammation, and redness induration) has been observed, as the first and unique adverse effect reported in the literature.http://dx.doi.org/10.1155/2014/150709
spellingShingle Murat Tonbul
Mujdat Adas
Taner Bekmezci
Ahmet Duran Kara
Intra-Articular Polyacrylamide Hydrogel Injections Are Not Innocent
Case Reports in Orthopedics
title Intra-Articular Polyacrylamide Hydrogel Injections Are Not Innocent
title_full Intra-Articular Polyacrylamide Hydrogel Injections Are Not Innocent
title_fullStr Intra-Articular Polyacrylamide Hydrogel Injections Are Not Innocent
title_full_unstemmed Intra-Articular Polyacrylamide Hydrogel Injections Are Not Innocent
title_short Intra-Articular Polyacrylamide Hydrogel Injections Are Not Innocent
title_sort intra articular polyacrylamide hydrogel injections are not innocent
url http://dx.doi.org/10.1155/2014/150709
work_keys_str_mv AT murattonbul intraarticularpolyacrylamidehydrogelinjectionsarenotinnocent
AT mujdatadas intraarticularpolyacrylamidehydrogelinjectionsarenotinnocent
AT tanerbekmezci intraarticularpolyacrylamidehydrogelinjectionsarenotinnocent
AT ahmetdurankara intraarticularpolyacrylamidehydrogelinjectionsarenotinnocent