A Turbidity Test Based Centrifugal Microfluidics Diagnostic System for Simultaneous Detection of HBV, HCV, and CMV
This paper presents a LAMP- (loop-mediated isothermal amplification-) based lab-on-disk optical system that allows the simultaneous detection of hepatitis B virus, hepatitis C virus, and cytomegalovirus. The various flow stages are controlled in the proposed system using different balance among cent...
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| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2015-01-01
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| Series: | Advances in Materials Science and Engineering |
| Online Access: | http://dx.doi.org/10.1155/2015/306708 |
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| author | Hung-Cheng Chang Yu-Tin Chao Jia-Yush Yen Ya-Lin Yu Chun-Nan Lee Bing-Ching Ho Kou-Chen Liu Jiunn Fang Chii-Wann Lin Jiun-Haw Lee |
| author_facet | Hung-Cheng Chang Yu-Tin Chao Jia-Yush Yen Ya-Lin Yu Chun-Nan Lee Bing-Ching Ho Kou-Chen Liu Jiunn Fang Chii-Wann Lin Jiun-Haw Lee |
| author_sort | Hung-Cheng Chang |
| collection | DOAJ |
| description | This paper presents a LAMP- (loop-mediated isothermal amplification-) based lab-on-disk optical system that allows the simultaneous detection of hepatitis B virus, hepatitis C virus, and cytomegalovirus. The various flow stages are controlled in the proposed system using different balance among centrifugal pumping, Coriolis pumping, and the capillary force. We have implemented a servo system for positioning and speed control for the heating and centrifugal pumping. We have also successfully employed a polymer light-emitting diode section for turbidity detection. The easy-to-use one-click system can perform diagnostics in less than 1 hour. |
| format | Article |
| id | doaj-art-26ebda8b5a784898b90c4dfc7f7de60e |
| institution | OA Journals |
| issn | 1687-8434 1687-8442 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Advances in Materials Science and Engineering |
| spelling | doaj-art-26ebda8b5a784898b90c4dfc7f7de60e2025-08-20T02:04:23ZengWileyAdvances in Materials Science and Engineering1687-84341687-84422015-01-01201510.1155/2015/306708306708A Turbidity Test Based Centrifugal Microfluidics Diagnostic System for Simultaneous Detection of HBV, HCV, and CMVHung-Cheng Chang0Yu-Tin Chao1Jia-Yush Yen2Ya-Lin Yu3Chun-Nan Lee4Bing-Ching Ho5Kou-Chen Liu6Jiunn Fang7Chii-Wann Lin8Jiun-Haw Lee9Department of Mechanical Engineering, National Taiwan University, Taipei 106, TaiwanDepartment of Mechanical Engineering, National Taiwan University, Taipei 106, TaiwanDepartment of Mechanical Engineering, National Taiwan University, Taipei 106, TaiwanDepartment of Mechanical Engineering, National Taiwan University, Taipei 106, TaiwanCollege of Medicine, National Taiwan University, Taipei 106, TaiwanCollege of Medicine, National Taiwan University, Taipei 106, TaiwanDepartment of Electronic Engineering, Chang Gung University, Taoyuan 333, TaiwanDepartment of Aerospace and System Engineering, Feng Chia University, Taichung 407, TaiwanInstitute of Biomedical Engineering, National Taiwan University, Taipei 106, TaiwanDepartment of Electronic Engineering, National Taiwan University, Taipei 106, TaiwanThis paper presents a LAMP- (loop-mediated isothermal amplification-) based lab-on-disk optical system that allows the simultaneous detection of hepatitis B virus, hepatitis C virus, and cytomegalovirus. The various flow stages are controlled in the proposed system using different balance among centrifugal pumping, Coriolis pumping, and the capillary force. We have implemented a servo system for positioning and speed control for the heating and centrifugal pumping. We have also successfully employed a polymer light-emitting diode section for turbidity detection. The easy-to-use one-click system can perform diagnostics in less than 1 hour.http://dx.doi.org/10.1155/2015/306708 |
| spellingShingle | Hung-Cheng Chang Yu-Tin Chao Jia-Yush Yen Ya-Lin Yu Chun-Nan Lee Bing-Ching Ho Kou-Chen Liu Jiunn Fang Chii-Wann Lin Jiun-Haw Lee A Turbidity Test Based Centrifugal Microfluidics Diagnostic System for Simultaneous Detection of HBV, HCV, and CMV Advances in Materials Science and Engineering |
| title | A Turbidity Test Based Centrifugal Microfluidics Diagnostic System for Simultaneous Detection of HBV, HCV, and CMV |
| title_full | A Turbidity Test Based Centrifugal Microfluidics Diagnostic System for Simultaneous Detection of HBV, HCV, and CMV |
| title_fullStr | A Turbidity Test Based Centrifugal Microfluidics Diagnostic System for Simultaneous Detection of HBV, HCV, and CMV |
| title_full_unstemmed | A Turbidity Test Based Centrifugal Microfluidics Diagnostic System for Simultaneous Detection of HBV, HCV, and CMV |
| title_short | A Turbidity Test Based Centrifugal Microfluidics Diagnostic System for Simultaneous Detection of HBV, HCV, and CMV |
| title_sort | turbidity test based centrifugal microfluidics diagnostic system for simultaneous detection of hbv hcv and cmv |
| url | http://dx.doi.org/10.1155/2015/306708 |
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