Mechanisms and diagnosis of myocardial ischemia in patients with intact coronary arteries
This article describes pathogenetic mechanisms underlying the occurrence of myocardial ischemia and angina attacks in patients without ischemic non-obstructive coronary artery (INOCA) based on coronary angiography. Groups of patients who need additional invasive diagnosis with intracoronary administ...
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| Format: | Article |
| Language: | English |
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TOV Chetverta Khvylia
2021-10-01
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| Series: | Кардіохірургія та інтервенційна кардіологія |
| Subjects: | |
| Online Access: | http://www.csic.com.ua/images/pdf/2021/3-2021/mechanisms-and-diagnosis-of-myocardial-ischemia-in-patients-with-intact-coronary-arteries.pdf |
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| author | V.A. Skybchyk Yu.P. Melen |
| author_facet | V.A. Skybchyk Yu.P. Melen |
| author_sort | V.A. Skybchyk |
| collection | DOAJ |
| description | This article describes pathogenetic mechanisms underlying the occurrence of myocardial ischemia and angina attacks in patients without ischemic non-obstructive coronary artery (INOCA) based on coronary angiography. Groups of patients who need additional invasive diagnosis with intracoronary administration of vasoactive agents (adenosine, acetylcholine) were identified. The diagnostic and technical features used during the invasive diagnostic procedure are presented in detail. The main indicators (coronary flow reserve, index of microvascular resistance, hyperemic microvascular resistance) are described. Particular attention is paid to the factors complicating interpretation of the results, as well as to the safety of this procedure. The information obtained during the invasive diagnostic procedure allows to determine the appropriate endotype of INOCA in order to make a correct diagnosis and prescribe effective drug treatment improving prognosis and quality of life. |
| format | Article |
| id | doaj-art-26eb71aef5374602a1f107418db1caa8 |
| institution | Kabale University |
| issn | 2305-3127 |
| language | English |
| publishDate | 2021-10-01 |
| publisher | TOV Chetverta Khvylia |
| record_format | Article |
| series | Кардіохірургія та інтервенційна кардіологія |
| spelling | doaj-art-26eb71aef5374602a1f107418db1caa82025-02-02T05:12:11ZengTOV Chetverta KhvyliaКардіохірургія та інтервенційна кардіологія2305-31272021-10-013162410.31928/2305-3127-2021.3.1624Mechanisms and diagnosis of myocardial ischemia in patients with intact coronary arteriesV.A. Skybchyk0Yu.P. Melen1Danylo Halytsky Lviv National Medical University, Lviv, UkraineLviv Clinical Emergency Hospital, Lviv, UkraineThis article describes pathogenetic mechanisms underlying the occurrence of myocardial ischemia and angina attacks in patients without ischemic non-obstructive coronary artery (INOCA) based on coronary angiography. Groups of patients who need additional invasive diagnosis with intracoronary administration of vasoactive agents (adenosine, acetylcholine) were identified. The diagnostic and technical features used during the invasive diagnostic procedure are presented in detail. The main indicators (coronary flow reserve, index of microvascular resistance, hyperemic microvascular resistance) are described. Particular attention is paid to the factors complicating interpretation of the results, as well as to the safety of this procedure. The information obtained during the invasive diagnostic procedure allows to determine the appropriate endotype of INOCA in order to make a correct diagnosis and prescribe effective drug treatment improving prognosis and quality of life.http://www.csic.com.ua/images/pdf/2021/3-2021/mechanisms-and-diagnosis-of-myocardial-ischemia-in-patients-with-intact-coronary-arteries.pdfintact coronary arteriescoronary angiographyinvasive diagnostic procedurevasospastic angina |
| spellingShingle | V.A. Skybchyk Yu.P. Melen Mechanisms and diagnosis of myocardial ischemia in patients with intact coronary arteries Кардіохірургія та інтервенційна кардіологія intact coronary arteries coronary angiography invasive diagnostic procedure vasospastic angina |
| title | Mechanisms and diagnosis of myocardial ischemia in patients with intact coronary arteries |
| title_full | Mechanisms and diagnosis of myocardial ischemia in patients with intact coronary arteries |
| title_fullStr | Mechanisms and diagnosis of myocardial ischemia in patients with intact coronary arteries |
| title_full_unstemmed | Mechanisms and diagnosis of myocardial ischemia in patients with intact coronary arteries |
| title_short | Mechanisms and diagnosis of myocardial ischemia in patients with intact coronary arteries |
| title_sort | mechanisms and diagnosis of myocardial ischemia in patients with intact coronary arteries |
| topic | intact coronary arteries coronary angiography invasive diagnostic procedure vasospastic angina |
| url | http://www.csic.com.ua/images/pdf/2021/3-2021/mechanisms-and-diagnosis-of-myocardial-ischemia-in-patients-with-intact-coronary-arteries.pdf |
| work_keys_str_mv | AT vaskybchyk mechanismsanddiagnosisofmyocardialischemiainpatientswithintactcoronaryarteries AT yupmelen mechanismsanddiagnosisofmyocardialischemiainpatientswithintactcoronaryarteries |