Streptococcus agalactiae-associated Urinary Tract Infections amongst Male Patients at a Tertiary Care Setting in Southwest India
Introduction: The occurrence of urinary tract infections (UTIs) caused by the group B Streptococcus (GBS) in females is well documented. On the contrary, the prevalence amongst males is infrequent, and studies from the Indian subcontinent are limited. This study aimed to determine the occurrence...
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Pasteur Institute of Iran
2022-03-01
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| Series: | Journal of Medical Microbiology and Infectious Diseases |
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| Online Access: | https://jommid.pasteur.ac.ir/article-1-374-en.html |
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| author | Asem Ali Ashraf1 Sreejith Govindan2 Nagalakshmi Narasimhaswamy2 Akshita Gupta1 |
| author_facet | Asem Ali Ashraf1 Sreejith Govindan2 Nagalakshmi Narasimhaswamy2 Akshita Gupta1 |
| author_sort | Asem Ali Ashraf1 |
| collection | DOAJ |
| description | Introduction: The occurrence of urinary tract infections (UTIs) caused by the
group B Streptococcus (GBS) in females is well documented. On the contrary,
the prevalence amongst males is infrequent, and studies from the Indian
subcontinent are limited. This study aimed to determine the occurrence of GBS
bacteriuria and its antibiotic susceptibility profile amongst male patients.
Methods: Clean-catch, midstream, catheterized, or voided urine samples from
patients were used for the study. Urinary samples from patients either admitted
or attended to a tertiary care center in Southwest India were promptly sent to the
laboratory for culture, identification, and antibiotic susceptibility test. Results:
A total of 16,190 urine specimens were processed during the 1-year study
period, of which 45 patients (0.27%), including 30 females (0.19%) and 15
males (0.09%), had GBS bacteriuria. The patients were mainly in the 19-45
years old group (53%). The most typical comorbidity was type 2 diabetes
mellitus (42%). The majority of the GBS isolates from male patients (>80%)
were susceptible to benzylpenicillin, ceftriaxone, ampicillin, and cotrimoxazole.
The isolates showed the least susceptibility to tetracycline (26.1%) Conclusion:
Though GBS-associated UTI amongst male patients is uncommon,
antimicrobial resistance amongst S. agalactiae isolates is widespread.
Nevertheless, antimicrobial resistance rates differ depending on the
geographical areas and study duration. Considering the emergence of drug
resistance in GBS, culture and antibiotic susceptibility testing patterns of all the
strains of GBS, even in asymptomatic patients with a low count, are
recommended. |
| format | Article |
| id | doaj-art-26e95131c2be487ca4e67c6d6f79bf63 |
| institution | DOAJ |
| issn | 2345-5349 2345-5330 |
| language | English |
| publishDate | 2022-03-01 |
| publisher | Pasteur Institute of Iran |
| record_format | Article |
| series | Journal of Medical Microbiology and Infectious Diseases |
| spelling | doaj-art-26e95131c2be487ca4e67c6d6f79bf632025-08-20T02:57:17ZengPasteur Institute of IranJournal of Medical Microbiology and Infectious Diseases2345-53492345-53302022-03-01101141810.52547/JoMMID.10.1.14Streptococcus agalactiae-associated Urinary Tract Infections amongst Male Patients at a Tertiary Care Setting in Southwest IndiaAsem Ali Ashraf10https://orcid.org/0000-0002-1028-0224Sreejith Govindan21https://orcid.org/0000-0002-2984-5053Nagalakshmi Narasimhaswamy22https://orcid.org/0000-0003-0495-3194Akshita Gupta13https://orcid.org/0000-0002-8687-73501Department of Microbiology, Kasturba Medical College, Manipal Academy of Higher Education2Department of Microbiology, Melaka Manipal Medical College, Manipal Academy of Higher Education2Department of Microbiology, Melaka Manipal Medical College, Manipal Academy of Higher Education1Department of Microbiology, Kasturba Medical College, Manipal Academy of Higher EducationIntroduction: The occurrence of urinary tract infections (UTIs) caused by the group B Streptococcus (GBS) in females is well documented. On the contrary, the prevalence amongst males is infrequent, and studies from the Indian subcontinent are limited. This study aimed to determine the occurrence of GBS bacteriuria and its antibiotic susceptibility profile amongst male patients. Methods: Clean-catch, midstream, catheterized, or voided urine samples from patients were used for the study. Urinary samples from patients either admitted or attended to a tertiary care center in Southwest India were promptly sent to the laboratory for culture, identification, and antibiotic susceptibility test. Results: A total of 16,190 urine specimens were processed during the 1-year study period, of which 45 patients (0.27%), including 30 females (0.19%) and 15 males (0.09%), had GBS bacteriuria. The patients were mainly in the 19-45 years old group (53%). The most typical comorbidity was type 2 diabetes mellitus (42%). The majority of the GBS isolates from male patients (>80%) were susceptible to benzylpenicillin, ceftriaxone, ampicillin, and cotrimoxazole. The isolates showed the least susceptibility to tetracycline (26.1%) Conclusion: Though GBS-associated UTI amongst male patients is uncommon, antimicrobial resistance amongst S. agalactiae isolates is widespread. Nevertheless, antimicrobial resistance rates differ depending on the geographical areas and study duration. Considering the emergence of drug resistance in GBS, culture and antibiotic susceptibility testing patterns of all the strains of GBS, even in asymptomatic patients with a low count, are recommended.https://jommid.pasteur.ac.ir/article-1-374-en.htmlstreptococcus agalactiaeurinary tract infectionsbacteraemiamalesantimicrobial resistance |
| spellingShingle | Asem Ali Ashraf1 Sreejith Govindan2 Nagalakshmi Narasimhaswamy2 Akshita Gupta1 Streptococcus agalactiae-associated Urinary Tract Infections amongst Male Patients at a Tertiary Care Setting in Southwest India Journal of Medical Microbiology and Infectious Diseases streptococcus agalactiae urinary tract infections bacteraemia males antimicrobial resistance |
| title | Streptococcus agalactiae-associated Urinary Tract Infections amongst Male Patients at a Tertiary Care Setting in Southwest India |
| title_full | Streptococcus agalactiae-associated Urinary Tract Infections amongst Male Patients at a Tertiary Care Setting in Southwest India |
| title_fullStr | Streptococcus agalactiae-associated Urinary Tract Infections amongst Male Patients at a Tertiary Care Setting in Southwest India |
| title_full_unstemmed | Streptococcus agalactiae-associated Urinary Tract Infections amongst Male Patients at a Tertiary Care Setting in Southwest India |
| title_short | Streptococcus agalactiae-associated Urinary Tract Infections amongst Male Patients at a Tertiary Care Setting in Southwest India |
| title_sort | streptococcus agalactiae associated urinary tract infections amongst male patients at a tertiary care setting in southwest india |
| topic | streptococcus agalactiae urinary tract infections bacteraemia males antimicrobial resistance |
| url | https://jommid.pasteur.ac.ir/article-1-374-en.html |
| work_keys_str_mv | AT asemaliashraf1 streptococcusagalactiaeassociatedurinarytractinfectionsamongstmalepatientsatatertiarycaresettinginsouthwestindia AT sreejithgovindan2 streptococcusagalactiaeassociatedurinarytractinfectionsamongstmalepatientsatatertiarycaresettinginsouthwestindia AT nagalakshminarasimhaswamy2 streptococcusagalactiaeassociatedurinarytractinfectionsamongstmalepatientsatatertiarycaresettinginsouthwestindia AT akshitagupta1 streptococcusagalactiaeassociatedurinarytractinfectionsamongstmalepatientsatatertiarycaresettinginsouthwestindia |