Oral Manifestations, Risk Factors and Management Strategies of COVID-19 Associated Mucormycosis in Tertiary Care Hospital

Background: Mucormycosis (black fungus) is an aggressive, life-threatening infectious disease-causing infiltration and by destroying the surrounding bone and soft tissue through vascular thrombosis and subsequent tissue infarction that may reach the brain with fatal complications. Its outbreak has b...

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Main Authors: Pankaj Goel, Jitendra Kumar, Anshul Rai, Prateek Shakti, Gunjan Chouksey
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2023-04-01
Series:Indian Journal of Dental Research
Subjects:
Online Access:https://journals.lww.com/10.4103/ijdr.ijdr_1062_21
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author Pankaj Goel
Jitendra Kumar
Anshul Rai
Prateek Shakti
Gunjan Chouksey
author_facet Pankaj Goel
Jitendra Kumar
Anshul Rai
Prateek Shakti
Gunjan Chouksey
author_sort Pankaj Goel
collection DOAJ
description Background: Mucormycosis (black fungus) is an aggressive, life-threatening infectious disease-causing infiltration and by destroying the surrounding bone and soft tissue through vascular thrombosis and subsequent tissue infarction that may reach the brain with fatal complications. Its outbreak has been assessed around the clock during the recent pandemic as post COVID-19 sequelae. Aims: To assess the risk factors, oral signs and symptoms, investigations, treatment and rehabilitation strategies amongst COVID-19 associated mucormycosis patients in a tertiary care hospital. Methods and Material: An observational, pilot study was carried out amongst 30 active or recent COVID-19 associated mucormycosis patients reporting in the Department of Dentistry of a tertiary care hospital in Bhopal over a period of 6 months. Statistical analysis was done using Kolmogorov-Smirnov test using the Statistical Package for Social Sciences, Version 16 software. Results: Study was done on 30 patients (80% males and 20% females) and their median age was 46 years. Predominant risk factor present was diabetes mellitus (90%) and steroid therapy (60%). Prime oral manifestations were toothache (90%), mobile teeth (83%), draining sinus (53%), palatal ulceration (43%) and para-sinusal pain (37%). Conclusions: Mucormycosis can cause serious oro-facial morbidity and mortality in COVID-19 patients. The current management strategy requires early diagnosis, prompt treatment and oral rehabilitation.
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spelling doaj-art-26e452deaacb42639d2f1c8ef5481b652025-02-09T09:39:31ZengWolters Kluwer Medknow PublicationsIndian Journal of Dental Research0970-92901998-36032023-04-0134215515810.4103/ijdr.ijdr_1062_21Oral Manifestations, Risk Factors and Management Strategies of COVID-19 Associated Mucormycosis in Tertiary Care HospitalPankaj GoelJitendra KumarAnshul RaiPrateek ShaktiGunjan ChoukseyBackground: Mucormycosis (black fungus) is an aggressive, life-threatening infectious disease-causing infiltration and by destroying the surrounding bone and soft tissue through vascular thrombosis and subsequent tissue infarction that may reach the brain with fatal complications. Its outbreak has been assessed around the clock during the recent pandemic as post COVID-19 sequelae. Aims: To assess the risk factors, oral signs and symptoms, investigations, treatment and rehabilitation strategies amongst COVID-19 associated mucormycosis patients in a tertiary care hospital. Methods and Material: An observational, pilot study was carried out amongst 30 active or recent COVID-19 associated mucormycosis patients reporting in the Department of Dentistry of a tertiary care hospital in Bhopal over a period of 6 months. Statistical analysis was done using Kolmogorov-Smirnov test using the Statistical Package for Social Sciences, Version 16 software. Results: Study was done on 30 patients (80% males and 20% females) and their median age was 46 years. Predominant risk factor present was diabetes mellitus (90%) and steroid therapy (60%). Prime oral manifestations were toothache (90%), mobile teeth (83%), draining sinus (53%), palatal ulceration (43%) and para-sinusal pain (37%). Conclusions: Mucormycosis can cause serious oro-facial morbidity and mortality in COVID-19 patients. The current management strategy requires early diagnosis, prompt treatment and oral rehabilitation.https://journals.lww.com/10.4103/ijdr.ijdr_1062_21black funguscovid-19mucormycosisoral manifestationsrisk factors
spellingShingle Pankaj Goel
Jitendra Kumar
Anshul Rai
Prateek Shakti
Gunjan Chouksey
Oral Manifestations, Risk Factors and Management Strategies of COVID-19 Associated Mucormycosis in Tertiary Care Hospital
Indian Journal of Dental Research
black fungus
covid-19
mucormycosis
oral manifestations
risk factors
title Oral Manifestations, Risk Factors and Management Strategies of COVID-19 Associated Mucormycosis in Tertiary Care Hospital
title_full Oral Manifestations, Risk Factors and Management Strategies of COVID-19 Associated Mucormycosis in Tertiary Care Hospital
title_fullStr Oral Manifestations, Risk Factors and Management Strategies of COVID-19 Associated Mucormycosis in Tertiary Care Hospital
title_full_unstemmed Oral Manifestations, Risk Factors and Management Strategies of COVID-19 Associated Mucormycosis in Tertiary Care Hospital
title_short Oral Manifestations, Risk Factors and Management Strategies of COVID-19 Associated Mucormycosis in Tertiary Care Hospital
title_sort oral manifestations risk factors and management strategies of covid 19 associated mucormycosis in tertiary care hospital
topic black fungus
covid-19
mucormycosis
oral manifestations
risk factors
url https://journals.lww.com/10.4103/ijdr.ijdr_1062_21
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