Relationship between Marriage and Prediabetes among Healthcare Workers: Mediating Effect of Triglycerides
<i>Background and Objectives</i>: In the literature, relationships between being married and having prediabetes or diabetes are inconsistent. We aimed to investigate whether marriage is a protective or risk factor for prediabetes and to uncover new insights into its impact on prediabetes...
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MDPI AG
2024-08-01
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| author | Yong-Hsin Chen Jia-June Lin Hsiu-Mei Tang Ching-Wen Yang Gwo-Ping Jong Yi-Sun Yang |
| author_facet | Yong-Hsin Chen Jia-June Lin Hsiu-Mei Tang Ching-Wen Yang Gwo-Ping Jong Yi-Sun Yang |
| author_sort | Yong-Hsin Chen |
| collection | DOAJ |
| description | <i>Background and Objectives</i>: In the literature, relationships between being married and having prediabetes or diabetes are inconsistent. We aimed to investigate whether marriage is a protective or risk factor for prediabetes and to uncover new insights into its impact on prediabetes. <i>Materials and Methods</i>: In this cross-sectional observational study, questionnaires were distributed by email to 1039 staff members who participated in an employee health check from a hospital affiliated with a medical university in Taiwan. Fasting blood glucose and triglyceride (TG) levels were checked and the questionnaires elicited basic demographic characteristics and included the Copenhagen Burnout Inventory and Nordic Musculoskeletal Questionnaire. The chi-square test or Fisher’s exact test, logistic regression, and mediation analysis were conducted for statistical analysis. <i>Results</i>: Among the group aged 20–37 years, married (OR = 1.89, 95%CI: 1.08, 3.33), obesity (OR = 2.95, 95%CI: 1.49, 5.83), neck and shoulder pain (OR = 1.31, 95%CI: 1.01, 1.69), and elevated TG levels (OR = 1.01, 95%CI: 1.00, 1.01) were independent risk factors for prediabetes (impaired fasting glucose). For those >38 years old, overweight (OR = 2.08, 95%CI: 1.27, 3.43), obesity (OR = 4.30, 95%CI: 2.38, 7.79), and elevated triglyceride (TG) (OR = 1.003, 95%CI: 1.00, 1.01) were the independent risk factors for impaired fasting glucose. Increased TG levels serve as a mediating factor (Z<sub>m</sub> = 2.64, <i>p</i> < 0.01) linking marriage to an increased risk of prediabetes for the group aged 20–37 years. <i>Conclusions</i>: TGs play a significant role in the association between marriage and prediabetes among the group aged 20–37 years. Therefore, dietary habits, especially those of young adult couples should be considered. Our findings connect marital status to prediabetes, facilitating advances in diabetes prevention. |
| format | Article |
| id | doaj-art-26e13484f1694845bb00f9da5f3e2d0f |
| institution | OA Journals |
| issn | 1010-660X 1648-9144 |
| language | English |
| publishDate | 2024-08-01 |
| publisher | MDPI AG |
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| series | Medicina |
| spelling | doaj-art-26e13484f1694845bb00f9da5f3e2d0f2025-08-20T01:55:39ZengMDPI AGMedicina1010-660X1648-91442024-08-01609141810.3390/medicina60091418Relationship between Marriage and Prediabetes among Healthcare Workers: Mediating Effect of TriglyceridesYong-Hsin Chen0Jia-June Lin1Hsiu-Mei Tang2Ching-Wen Yang3Gwo-Ping Jong4Yi-Sun Yang5The Department of Health Policy and Management, Chung Shan Medical University, Taichung 402, TaiwanNursing Department, Chung Shan Medical University Hospital, Taichung 402, TaiwanDepartment of Occupational Safety and Health, Chung Shan Medical University Hospital, Taichung 402, TaiwanDepartment of Occupational Safety and Health, Chung Shan Medical University Hospital, Taichung 402, TaiwanDepartment of Internal Medicine, Chung Shan Medical University Hospital, Taichung 402, TaiwanDepartment of Internal Medicine, Chung Shan Medical University Hospital, Taichung 402, Taiwan<i>Background and Objectives</i>: In the literature, relationships between being married and having prediabetes or diabetes are inconsistent. We aimed to investigate whether marriage is a protective or risk factor for prediabetes and to uncover new insights into its impact on prediabetes. <i>Materials and Methods</i>: In this cross-sectional observational study, questionnaires were distributed by email to 1039 staff members who participated in an employee health check from a hospital affiliated with a medical university in Taiwan. Fasting blood glucose and triglyceride (TG) levels were checked and the questionnaires elicited basic demographic characteristics and included the Copenhagen Burnout Inventory and Nordic Musculoskeletal Questionnaire. The chi-square test or Fisher’s exact test, logistic regression, and mediation analysis were conducted for statistical analysis. <i>Results</i>: Among the group aged 20–37 years, married (OR = 1.89, 95%CI: 1.08, 3.33), obesity (OR = 2.95, 95%CI: 1.49, 5.83), neck and shoulder pain (OR = 1.31, 95%CI: 1.01, 1.69), and elevated TG levels (OR = 1.01, 95%CI: 1.00, 1.01) were independent risk factors for prediabetes (impaired fasting glucose). For those >38 years old, overweight (OR = 2.08, 95%CI: 1.27, 3.43), obesity (OR = 4.30, 95%CI: 2.38, 7.79), and elevated triglyceride (TG) (OR = 1.003, 95%CI: 1.00, 1.01) were the independent risk factors for impaired fasting glucose. Increased TG levels serve as a mediating factor (Z<sub>m</sub> = 2.64, <i>p</i> < 0.01) linking marriage to an increased risk of prediabetes for the group aged 20–37 years. <i>Conclusions</i>: TGs play a significant role in the association between marriage and prediabetes among the group aged 20–37 years. Therefore, dietary habits, especially those of young adult couples should be considered. Our findings connect marital status to prediabetes, facilitating advances in diabetes prevention.https://www.mdpi.com/1648-9144/60/9/1418diabetesprediabetesimpaired fasting glucosetriglyceridesmarriageobesity |
| spellingShingle | Yong-Hsin Chen Jia-June Lin Hsiu-Mei Tang Ching-Wen Yang Gwo-Ping Jong Yi-Sun Yang Relationship between Marriage and Prediabetes among Healthcare Workers: Mediating Effect of Triglycerides Medicina diabetes prediabetes impaired fasting glucose triglycerides marriage obesity |
| title | Relationship between Marriage and Prediabetes among Healthcare Workers: Mediating Effect of Triglycerides |
| title_full | Relationship between Marriage and Prediabetes among Healthcare Workers: Mediating Effect of Triglycerides |
| title_fullStr | Relationship between Marriage and Prediabetes among Healthcare Workers: Mediating Effect of Triglycerides |
| title_full_unstemmed | Relationship between Marriage and Prediabetes among Healthcare Workers: Mediating Effect of Triglycerides |
| title_short | Relationship between Marriage and Prediabetes among Healthcare Workers: Mediating Effect of Triglycerides |
| title_sort | relationship between marriage and prediabetes among healthcare workers mediating effect of triglycerides |
| topic | diabetes prediabetes impaired fasting glucose triglycerides marriage obesity |
| url | https://www.mdpi.com/1648-9144/60/9/1418 |
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