Exploring the role of EMT in ovarian cancer progression using a multiscale mathematical model
Abstract Epithelial-to-mesenchymal transition (EMT) plays a key role in the progression of cancer tumours, significantly reducing the success of treatment. EMT occurs when a cell undergoes phenotypical changes, resulting in enhanced drug resistance, higher cell plasticity, and increased metastatic a...
Saved in:
| Main Authors: | Samuel Oliver, Michael Williams, Mohit Kumar Jolly, Deyarina Gonzalez, Gibin Powathil |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-04-01
|
| Series: | npj Systems Biology and Applications |
| Online Access: | https://doi.org/10.1038/s41540-025-00508-y |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Strategies of eradicating glioma cells: a multi-scale mathematical model with MiR-451-AMPK-mTOR control.
by: Yangjin Kim, et al.
Published: (2015-01-01) -
Exploring the role of NAT10 in regulating EMT and JAK2/STAT3 pathway activation in cervical cancer progression
by: Yawen Chen, et al.
Published: (2025-05-01) -
SATB1 overexpression regulates the development and progression in bladder cancer through EMT.
by: Feng Wan, et al.
Published: (2015-01-01) -
PTTG1 promotes M2 macrophage polarization via the cGMP-PKG signaling pathway and facilitates EMT progression in human epithelial ovarian cancer cells
by: Liang Tian, et al.
Published: (2025-05-01) -
The CXCR4 antagonist R54 targets epithelial-mesenchymal transition (EMT) in human ovarian cancer cells.
by: Daniela Russo, et al.
Published: (2024-01-01)