Research advances of vasohibin family regulating angiogenesis in kidney diseases
Vascular endothelial injury of renal microvessels and a decrease of peritubular capillaries are vital in the pathogenesis of acute and chronic renal disease.Capable of endodermal regulation of angiogenesis，vasohibin family （VASH） plays an important role in such diseases as acute kidney injury，chroni...
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| Format: | Article |
| Language: | zho |
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Editorial Department of Journal of Clinical Nephrology
2022-04-01
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| Series: | Linchuang shenzangbing zazhi |
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| Online Access: | http://www.lcszb.com/thesisDetails#10.3969/j.issn.1671-2390.2022.04.014 |
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| _version_ | 1850187163426095104 |
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| author | Xiong Yan Xu Chuan-wen Xu Yan-mei |
| author_facet | Xiong Yan Xu Chuan-wen Xu Yan-mei |
| author_sort | Xiong Yan |
| collection | DOAJ |
| description | Vascular endothelial injury of renal microvessels and a decrease of peritubular capillaries are vital in the pathogenesis of acute and chronic renal disease.Capable of endodermal regulation of angiogenesis，vasohibin family （VASH） plays an important role in such diseases as acute kidney injury，chronic kidney disease，diabetic nephropathy and renal tumor.Many studies have suggested that VASH is expected to be a molecular marker for diagnosing and treating kidney diseases and it will become an effective protein factor for molecular targeted therapy.This review summarized structural characteristics，biological activities and related studies of vasohibin family members in kidney diseases. |
| format | Article |
| id | doaj-art-26d1c3566a3a455cab3fdab83ca487a3 |
| institution | OA Journals |
| issn | 1671-2390 |
| language | zho |
| publishDate | 2022-04-01 |
| publisher | Editorial Department of Journal of Clinical Nephrology |
| record_format | Article |
| series | Linchuang shenzangbing zazhi |
| spelling | doaj-art-26d1c3566a3a455cab3fdab83ca487a32025-08-20T02:16:10ZzhoEditorial Department of Journal of Clinical NephrologyLinchuang shenzangbing zazhi1671-23902022-04-012234434825398572Research advances of vasohibin family regulating angiogenesis in kidney diseasesXiong YanXu Chuan-wenXu Yan-meiVascular endothelial injury of renal microvessels and a decrease of peritubular capillaries are vital in the pathogenesis of acute and chronic renal disease.Capable of endodermal regulation of angiogenesis，vasohibin family （VASH） plays an important role in such diseases as acute kidney injury，chronic kidney disease，diabetic nephropathy and renal tumor.Many studies have suggested that VASH is expected to be a molecular marker for diagnosing and treating kidney diseases and it will become an effective protein factor for molecular targeted therapy.This review summarized structural characteristics，biological activities and related studies of vasohibin family members in kidney diseases.http://www.lcszb.com/thesisDetails#10.3969/j.issn.1671-2390.2022.04.014VasohibinKidney diseaseAngiogenesisNegative feedbackVascular endothelial growth factor |
| spellingShingle | Xiong Yan Xu Chuan-wen Xu Yan-mei Research advances of vasohibin family regulating angiogenesis in kidney diseases Linchuang shenzangbing zazhi Vasohibin Kidney disease Angiogenesis Negative feedback Vascular endothelial growth factor |
| title | Research advances of vasohibin family regulating angiogenesis in kidney diseases |
| title_full | Research advances of vasohibin family regulating angiogenesis in kidney diseases |
| title_fullStr | Research advances of vasohibin family regulating angiogenesis in kidney diseases |
| title_full_unstemmed | Research advances of vasohibin family regulating angiogenesis in kidney diseases |
| title_short | Research advances of vasohibin family regulating angiogenesis in kidney diseases |
| title_sort | research advances of vasohibin family regulating angiogenesis in kidney diseases |
| topic | Vasohibin Kidney disease Angiogenesis Negative feedback Vascular endothelial growth factor |
| url | http://www.lcszb.com/thesisDetails#10.3969/j.issn.1671-2390.2022.04.014 |
| work_keys_str_mv | AT xiongyan researchadvancesofvasohibinfamilyregulatingangiogenesisinkidneydiseases AT xuchuanwen researchadvancesofvasohibinfamilyregulatingangiogenesisinkidneydiseases AT xuyanmei researchadvancesofvasohibinfamilyregulatingangiogenesisinkidneydiseases |