Stretching and immobilizing a single DNA molecule on a glass surface using pressure flow in a microchannel for super-resolution imaging
Single-DNA analysis combines fluorescence microscopy with a method of stretching a single DNA molecule from its random coil shape to a linear shape. Although super-resolution imaging methods can be used for analyzing the DNA with a higher lateral resolution, these methods require several seconds to...
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Main Authors: | Naoki Azuma, Ryotaro Suzuki, Kenji Fukuzawa, Shintaro Itoh, Hedong Zhang |
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Format: | Article |
Language: | English |
Published: |
AIP Publishing LLC
2025-01-01
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Series: | AIP Advances |
Online Access: | http://dx.doi.org/10.1063/5.0223375 |
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