RAS in Pregnancy and Preeclampsia and Eclampsia

Preeclampsia is a common disease of pregnancy characterized by the presence of hypertension and commitment of many organs, including the brain, secondary to generalized endothelial dysfunction. Its etiology is not known precisely, but it involved several factors, highlighting the renin angiotensin s...

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Main Authors: M. Rodriguez, J. Moreno, J. Hasbun
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:International Journal of Hypertension
Online Access:http://dx.doi.org/10.1155/2012/739274
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author M. Rodriguez
J. Moreno
J. Hasbun
author_facet M. Rodriguez
J. Moreno
J. Hasbun
author_sort M. Rodriguez
collection DOAJ
description Preeclampsia is a common disease of pregnancy characterized by the presence of hypertension and commitment of many organs, including the brain, secondary to generalized endothelial dysfunction. Its etiology is not known precisely, but it involved several factors, highlighting the renin angiotensin system (RAS), which would have an important role in the origin of multisystem involvement. This paper reviews the evidence supporting the involvement of RAS in triggering the disease, in addition to the components of this system that would be involved and how it eventually produces brain engagement.
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institution Kabale University
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series International Journal of Hypertension
spelling doaj-art-26b1841b411d4715a241c4e44fe7c5182025-02-03T01:23:08ZengWileyInternational Journal of Hypertension2090-03842090-03922012-01-01201210.1155/2012/739274739274RAS in Pregnancy and Preeclampsia and EclampsiaM. Rodriguez0J. Moreno1J. Hasbun2Department of Obstetrics and Gynecology, Universidad de Valparaiso, 2341131 Valparaiso, ChileDepartment of Obstetrics and Gynecology, Universidad de Valparaiso, 2341131 Valparaiso, ChileFetal Medicine Unit, Hospital Clinico Universidad de Chile, 8380456 Santiago, ChilePreeclampsia is a common disease of pregnancy characterized by the presence of hypertension and commitment of many organs, including the brain, secondary to generalized endothelial dysfunction. Its etiology is not known precisely, but it involved several factors, highlighting the renin angiotensin system (RAS), which would have an important role in the origin of multisystem involvement. This paper reviews the evidence supporting the involvement of RAS in triggering the disease, in addition to the components of this system that would be involved and how it eventually produces brain engagement.http://dx.doi.org/10.1155/2012/739274
spellingShingle M. Rodriguez
J. Moreno
J. Hasbun
RAS in Pregnancy and Preeclampsia and Eclampsia
International Journal of Hypertension
title RAS in Pregnancy and Preeclampsia and Eclampsia
title_full RAS in Pregnancy and Preeclampsia and Eclampsia
title_fullStr RAS in Pregnancy and Preeclampsia and Eclampsia
title_full_unstemmed RAS in Pregnancy and Preeclampsia and Eclampsia
title_short RAS in Pregnancy and Preeclampsia and Eclampsia
title_sort ras in pregnancy and preeclampsia and eclampsia
url http://dx.doi.org/10.1155/2012/739274
work_keys_str_mv AT mrodriguez rasinpregnancyandpreeclampsiaandeclampsia
AT jmoreno rasinpregnancyandpreeclampsiaandeclampsia
AT jhasbun rasinpregnancyandpreeclampsiaandeclampsia