Metabolic Changes in Patients with Premature Ovarian Insufficiency: Adipose Tissue Focus—A Narrative Review

Metabolic Changes in Patients with Premature Ovarian Insufficiency: Adipose Tissue Focus—A Narrative Review

<b>Background:</b> Estrogen plays a crucial role in adipose tissue homeostasis, influencing fat distribution, lipid metabolism, and insulin sensitivity. Through estrogen receptor (ER) activation, particularly ERα, estradiol (E2) regulates adipogenesis, inhibits adipocyte hypertrophy, and...

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Main Authors: Miriam Sánchez-García, Kapy León-Wu, Regina de Miguel-Ibáñez, Nitzia López-Juárez, Claudia Ramírez-Rentería, Etual Espinosa-Cárdenas, Ernesto Sosa-Eroza, Manuel R. García-Sáenz
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Metabolites
Subjects:
primary ovarian insufficiency
estrogens
adipose tissue
lipid metabolism
Online Access:https://www.mdpi.com/2218-1989/15/4/242
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