Lamins regulate cancer cell plasticity and chemosensitivity

Lamins regulate cancer cell plasticity and chemosensitivity

BackgroundStem cell plasticity plays key roles in mammalian organogenesis, tissue homeostasis, and carcinogenesis. Given its tolerance to anti-tumor therapy and its promotion on immunosuppressive microenvironment, cancer cell plasticity is a major contributor to cancer recurrence and metastasis. It...

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Bibliographic Details
Main Authors:	Guofang Chen, Tingyi Wei, Ao Huang, Junwei Shen, Furong Ju, Shichao Huang, Haisen Li
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-07-01
Series:	Frontiers in Oncology
Subjects:	lamin cancer cell plasticity PD-L1 chemosensitivity HIF-1 signaling
Online Access:	https://www.frontiersin.org/articles/10.3389/fonc.2025.1599175/full
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