A systems biology approach to define SARS-CoV-2 correlates of protection
Abstract Correlates of protection (CoPs) for SARS-CoV-2 have yet to be sufficiently defined. This study uses the machine learning platform, SIMON, to accurately predict the immunological parameters that reduced clinical pathology or viral load following SARS-CoV-2 challenge in a cohort of 90 non-hum...
Saved in:
| Main Authors: | Caolann Brady, Tom Tipton, Oliver Carnell, Stephanie Longet, Karen Gooch, Yper Hall, Javier Salguero, Adriana Tomic, Miles Carroll |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-04-01
|
| Series: | npj Vaccines |
| Online Access: | https://doi.org/10.1038/s41541-025-01103-2 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Hamsters immunized with formalin-inactivated SARS-CoV-2 develop accelerated lung histopathological lesions and Th2-biased response following infection
by: Rineke de Jong, et al.
Published: (2025-07-01) -
Hypoxia inducible factors regulate infectious SARS-CoV-2, epithelial damage and respiratory symptoms in a hamster COVID-19 model.
by: Peter A C Wing, et al.
Published: (2022-09-01) -
Phenotypic heterogeneity defines B cell responses to repeated SARS-CoV-2 exposures through vaccination and infection
by: Lela Kardava, et al.
Published: (2025-04-01) -
Defining the Syrian hamster as a highly susceptible preclinical model for SARS-CoV-2 infection
by: Kyle Rosenke, et al.
Published: (2020-01-01) -
Detection of breastmilk antibodies targeting SARS-CoV-2 nucleocapsid, spike and receptor-binding-domain antigens
by: D. M. Favara, et al.
Published: (2020-01-01)