Spatial immunogenomic patterns associated with lymph node metastasis in lung adenocarcinoma

Spatial immunogenomic patterns associated with lymph node metastasis in lung adenocarcinoma

Abstract Background Lung adenocarcinoma (LUAD) with lymph node (LN) metastasis is linked to poor prognosis, yet the underlying mechanisms remain largely undefined. This study aimed to elucidate the immunogenomic landscape associated with LN metastasis in LUAD. Methods We employed broad-panel next-ge...

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Bibliographic Details
Main Authors: Fanjie Meng, Hao Li, Ruoyi Jin, Airong Yang, Hao Luo, Xiao Li, Peiyu Wang, Yaxing Zhao, Olga Chervova, Kaicheng Tang, Sida Cheng, Bin Hu, Yun Li, Jianpeng Sheng, Fan Yang, David Carbone, Kezhong Chen, Jun Wang
Format: Article
Language:English
Published: BMC 2024-10-01
Series:Experimental Hematology & Oncology
Subjects:
Lung adenocarcinoma lymph node metastasis
Genomic signatures
Tumor immune microenvironment
Spatial immunogenomic patterns
Online Access:https://doi.org/10.1186/s40164-024-00574-8
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