Second brain: reviewing the gut microbiome’s role in lifestyle diseases

The recent COVID-19 pandemic has highlighted another silent pandemic: lifestyle diseases. Conditions, such as cardiovascular diseases, anxiety, and type 2 diabetes (T2D), are increasingly becoming public health threats, affecting even younger populations worldwide. In recent years, extensive researc...

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Main Authors: Hindol Ray, Janatum Khatum, Srijan Haldar, Priyanka Bhowmik
Format: Article
Language:English
Published: Termedia Publishing House 2025-03-01
Series:BioTechnologia
Subjects:
Online Access:https://www.biotechnologia-journal.org/Second-brain-reviewing-the-gut-microbiome-s-role-in-lifestyle-diseases,195495,0,2.html
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author Hindol Ray
Janatum Khatum
Srijan Haldar
Priyanka Bhowmik
author_facet Hindol Ray
Janatum Khatum
Srijan Haldar
Priyanka Bhowmik
author_sort Hindol Ray
collection DOAJ
description The recent COVID-19 pandemic has highlighted another silent pandemic: lifestyle diseases. Conditions, such as cardiovascular diseases, anxiety, and type 2 diabetes (T2D), are increasingly becoming public health threats, affecting even younger populations worldwide. In recent years, extensive research has uncovered the pivotal role of the human gut microbiome in various aspects of human physiology, including metabolism, cellular homeostasis, immune defense, and disease development. The gut microbiome, often referred to as the “second brain,” is now recognized as a key player in health and disease. Lifestyle factors such as diet, mental health, stress, exercise, and others significantly influence the composition of the gut microbiome. Imbalances in this composition, termed “dysbiosis,” have been linked to a wide range of diseases, including cancer, cardiovascular diseases, obesity, T2D, asthma, and neurological disorders like Alzheimer’s and Parkinson’s disease. These findings underscore the profound influence of gut microbiome health on overall well-being. A working understanding of the gut microbiome’s composition and its impact on disease processes is crucial for the advancement of personalized or precision medicine. This review article aims to explore recent advancements in the field, shedding light on how the gut microbiome contributes to the development and prognosis of lifestyle diseases.
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publishDate 2025-03-01
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spelling doaj-art-26806ff9924e4108a3cef2bd050d7ffa2025-08-20T02:30:32ZengTermedia Publishing HouseBioTechnologia0860-77962353-94612025-03-01106110312210.5114/bta/195495195495Second brain: reviewing the gut microbiome’s role in lifestyle diseasesHindol Ray0Janatum Khatum1Srijan Haldar2Priyanka Bhowmik3Department of Biotechnology, Swami Vivekananda University, Barrackpore, West Bengal, IndiaDepartment of Biotechnology, Swami Vivekananda University, Barrackpore, West Bengal, IndiaDepartment of Biological Sciences, Adamas University, Kolkata, West Bengal, IndiaDepartment of Biological Sciences, Adamas University, Kolkata, West Bengal, IndiaThe recent COVID-19 pandemic has highlighted another silent pandemic: lifestyle diseases. Conditions, such as cardiovascular diseases, anxiety, and type 2 diabetes (T2D), are increasingly becoming public health threats, affecting even younger populations worldwide. In recent years, extensive research has uncovered the pivotal role of the human gut microbiome in various aspects of human physiology, including metabolism, cellular homeostasis, immune defense, and disease development. The gut microbiome, often referred to as the “second brain,” is now recognized as a key player in health and disease. Lifestyle factors such as diet, mental health, stress, exercise, and others significantly influence the composition of the gut microbiome. Imbalances in this composition, termed “dysbiosis,” have been linked to a wide range of diseases, including cancer, cardiovascular diseases, obesity, T2D, asthma, and neurological disorders like Alzheimer’s and Parkinson’s disease. These findings underscore the profound influence of gut microbiome health on overall well-being. A working understanding of the gut microbiome’s composition and its impact on disease processes is crucial for the advancement of personalized or precision medicine. This review article aims to explore recent advancements in the field, shedding light on how the gut microbiome contributes to the development and prognosis of lifestyle diseases.https://www.biotechnologia-journal.org/Second-brain-reviewing-the-gut-microbiome-s-role-in-lifestyle-diseases,195495,0,2.htmlgut microbiomecancerobesitylifestyle diseasesdiabetesalzheimer’s disease
spellingShingle Hindol Ray
Janatum Khatum
Srijan Haldar
Priyanka Bhowmik
Second brain: reviewing the gut microbiome’s role in lifestyle diseases
BioTechnologia
gut microbiome
cancer
obesity
lifestyle diseases
diabetes
alzheimer’s disease
title Second brain: reviewing the gut microbiome’s role in lifestyle diseases
title_full Second brain: reviewing the gut microbiome’s role in lifestyle diseases
title_fullStr Second brain: reviewing the gut microbiome’s role in lifestyle diseases
title_full_unstemmed Second brain: reviewing the gut microbiome’s role in lifestyle diseases
title_short Second brain: reviewing the gut microbiome’s role in lifestyle diseases
title_sort second brain reviewing the gut microbiome s role in lifestyle diseases
topic gut microbiome
cancer
obesity
lifestyle diseases
diabetes
alzheimer’s disease
url https://www.biotechnologia-journal.org/Second-brain-reviewing-the-gut-microbiome-s-role-in-lifestyle-diseases,195495,0,2.html
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