The relationship between energy intake and asthma in Americans aged 1–18 years: a cross-sectional study

Abstract Objective The objective of this study was to investigate the effects of total dietary energy intake on asthma. Study selection. The study was a retrospective cross-sectional study of Americans aged 1–18 year. Comprehensive demographic, dietary, examination, laboratory, and asthma questionna...

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Main Authors: Lin jun Du, Chao Che, Qian Liu, Xiaolan Zhang, Ning Feng, Lifang Chen, Lili Wang
Format: Article
Language:English
Published: BMC 2025-03-01
Series:BMC Pediatrics
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Online Access:https://doi.org/10.1186/s12887-025-05552-5
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author Lin jun Du
Chao Che
Qian Liu
Xiaolan Zhang
Ning Feng
Lifang Chen
Lili Wang
author_facet Lin jun Du
Chao Che
Qian Liu
Xiaolan Zhang
Ning Feng
Lifang Chen
Lili Wang
author_sort Lin jun Du
collection DOAJ
description Abstract Objective The objective of this study was to investigate the effects of total dietary energy intake on asthma. Study selection. The study was a retrospective cross-sectional study of Americans aged 1–18 year. Comprehensive demographic, dietary, examination, laboratory, and asthma questionnaire data were collected for each participant. Multivariate logistic regression, restricted triple spline curves, threshold effects, and stratified analyses were used for analysis. Results Of 12,090 participants, 1,893 (15.66%) had a diagnosis of asthma. After accounting for potential confounders, compared with the group with the lowest energy intake (Q1), groups 2 (Q2), groups 3 (Q3), and groups 4 (Q4) had adjusted odds ratios (ORs) of 0.72 (0.62–0.85), 0.63 (0.51–0.77) and 0.55 (0.43–0.7) for asthma. The relationship between total energy intake and asthma showed an L-shaped curve (p = 0.001). The results were further verified by stratification and sensitivity analyses. In the threshold analysis, we found that the saturation effect was reached at a total energy intake of 56.442 kcal/kg/day with an OR of 0.981 (0.973–0.989). Conclusion The prevalence of asthma in Americans aged 1–18 years was associated with total dietary energy intake in an L-shaped curve, with a significant turning point found at approximately 56.442 kcal/kg/day.
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spelling doaj-art-267d7fbca16546c3b2f9ca42d00a46a62025-08-20T03:01:55ZengBMCBMC Pediatrics1471-24312025-03-0125111010.1186/s12887-025-05552-5The relationship between energy intake and asthma in Americans aged 1–18 years: a cross-sectional studyLin jun Du0Chao Che1Qian Liu2Xiaolan Zhang3Ning Feng4Lifang Chen5Lili Wang6The Third People’s Hospital of Liaocheng CityQilu Hospital of Shandong UniversityJinan Fifth People’s HospitalThe Third People’s Hospital of Liaocheng CityThe Third People’s Hospital of Liaocheng CityThe Third People’s Hospital of Liaocheng CityMaternal and Child Health Center, Chiping DistrictAbstract Objective The objective of this study was to investigate the effects of total dietary energy intake on asthma. Study selection. The study was a retrospective cross-sectional study of Americans aged 1–18 year. Comprehensive demographic, dietary, examination, laboratory, and asthma questionnaire data were collected for each participant. Multivariate logistic regression, restricted triple spline curves, threshold effects, and stratified analyses were used for analysis. Results Of 12,090 participants, 1,893 (15.66%) had a diagnosis of asthma. After accounting for potential confounders, compared with the group with the lowest energy intake (Q1), groups 2 (Q2), groups 3 (Q3), and groups 4 (Q4) had adjusted odds ratios (ORs) of 0.72 (0.62–0.85), 0.63 (0.51–0.77) and 0.55 (0.43–0.7) for asthma. The relationship between total energy intake and asthma showed an L-shaped curve (p = 0.001). The results were further verified by stratification and sensitivity analyses. In the threshold analysis, we found that the saturation effect was reached at a total energy intake of 56.442 kcal/kg/day with an OR of 0.981 (0.973–0.989). Conclusion The prevalence of asthma in Americans aged 1–18 years was associated with total dietary energy intake in an L-shaped curve, with a significant turning point found at approximately 56.442 kcal/kg/day.https://doi.org/10.1186/s12887-025-05552-5L-shaped relationshipCross-sectional studyAsthmaChildrenDietEnergy intake
spellingShingle Lin jun Du
Chao Che
Qian Liu
Xiaolan Zhang
Ning Feng
Lifang Chen
Lili Wang
The relationship between energy intake and asthma in Americans aged 1–18 years: a cross-sectional study
BMC Pediatrics
L-shaped relationship
Cross-sectional study
Asthma
Children
Diet
Energy intake
title The relationship between energy intake and asthma in Americans aged 1–18 years: a cross-sectional study
title_full The relationship between energy intake and asthma in Americans aged 1–18 years: a cross-sectional study
title_fullStr The relationship between energy intake and asthma in Americans aged 1–18 years: a cross-sectional study
title_full_unstemmed The relationship between energy intake and asthma in Americans aged 1–18 years: a cross-sectional study
title_short The relationship between energy intake and asthma in Americans aged 1–18 years: a cross-sectional study
title_sort relationship between energy intake and asthma in americans aged 1 18 years a cross sectional study
topic L-shaped relationship
Cross-sectional study
Asthma
Children
Diet
Energy intake
url https://doi.org/10.1186/s12887-025-05552-5
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