Insecticide Resistance in Agricultural Pests: Mechanisms, Case Studies, and Future Directions

Pesticide resistance is an escalating global challenge that threatens agricultural productivity, food security, and the sustainability of pest control methods. Over 600 insect species have developed resistance, compromising the effectiveness of chemical controls and exacerbating pest outbreaks. Spe...

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Main Authors: Ihsan Khudhair, Naseer Malaky Abbood, Yasser Ahmed Mahmoud El-Amier
Format: Article
Language:English
Published: University of Thi-Qar 2025-06-01
Series:مجلة علوم ذي قار
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Online Access:https://jsci.utq.edu.iq/index.php/main/article/view/1381
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author Ihsan Khudhair
Naseer Malaky Abbood
Yasser Ahmed Mahmoud El-Amier
author_facet Ihsan Khudhair
Naseer Malaky Abbood
Yasser Ahmed Mahmoud El-Amier
author_sort Ihsan Khudhair
collection DOAJ
description Pesticide resistance is an escalating global challenge that threatens agricultural productivity, food security, and the sustainability of pest control methods. Over 600 insect species have developed resistance, compromising the effectiveness of chemical controls and exacerbating pest outbreaks. Species such as Helicoverpa armigera and Bemisia tabaci serve as prominent examples of pests displaying this growing resistance problem. This study aims to explore the underlying mechanisms of pesticide resistance in key agricultural pests, identify the major contributing factors, assess the effectiveness of current management strategies, and examine potential future tools and technologies for combating resistance. The study integrates data from global case studies, specifically focusing on Helicoverpa armigera in India and Bemisia tabaci in China. It also synthesizes information on various resistance mechanisms, including metabolic, target-site, penetration, and behavioral processes. Several resistance management strategies, such as pesticide rotation, integrated pest management (IPM), and refuge policies, are evaluated for their effectiveness. Metabolic and target-site resistance mechanisms are particularly prevalent in resistant insect populations. Contributing factors include overuse of single pesticide classes, sub-lethal dosages, inadequate treatment regimens, and monoculture farming. IPM and pesticide rotation employing different modes of action are among the most effective current strategies. Emerging technologies RNA interference (RNAi) and CRISPR gene editing , offer promising new approaches. Addressing pesticide resistance requires a comprehensive, multi-faceted strategy that incorporates genetic tools, real-time monitoring, biopesticide development, and stronger regulatory frameworks. International cooperation, farmer education, and scientifically informed policies will be critical to future success.
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spelling doaj-art-267ba445df6f4de6bb3d3b0a6c59ea682025-08-20T02:39:38ZengUniversity of Thi-Qarمجلة علوم ذي قار1991-86902709-02562025-06-0112110.32792/utq/utjsci/v12i1.1381Insecticide Resistance in Agricultural Pests: Mechanisms, Case Studies, and Future DirectionsIhsan Khudhair0Naseer Malaky Abbood1Yasser Ahmed Mahmoud El-Amier2Faculty of Science/University of Thi-QarThi-Qar Education Directorate, Ministry of Education, Thi-Qar, IraqBotany Department,Faculty of Science, Mansoura University,Mansoura,Egypt. Pesticide resistance is an escalating global challenge that threatens agricultural productivity, food security, and the sustainability of pest control methods. Over 600 insect species have developed resistance, compromising the effectiveness of chemical controls and exacerbating pest outbreaks. Species such as Helicoverpa armigera and Bemisia tabaci serve as prominent examples of pests displaying this growing resistance problem. This study aims to explore the underlying mechanisms of pesticide resistance in key agricultural pests, identify the major contributing factors, assess the effectiveness of current management strategies, and examine potential future tools and technologies for combating resistance. The study integrates data from global case studies, specifically focusing on Helicoverpa armigera in India and Bemisia tabaci in China. It also synthesizes information on various resistance mechanisms, including metabolic, target-site, penetration, and behavioral processes. Several resistance management strategies, such as pesticide rotation, integrated pest management (IPM), and refuge policies, are evaluated for their effectiveness. Metabolic and target-site resistance mechanisms are particularly prevalent in resistant insect populations. Contributing factors include overuse of single pesticide classes, sub-lethal dosages, inadequate treatment regimens, and monoculture farming. IPM and pesticide rotation employing different modes of action are among the most effective current strategies. Emerging technologies RNA interference (RNAi) and CRISPR gene editing , offer promising new approaches. Addressing pesticide resistance requires a comprehensive, multi-faceted strategy that incorporates genetic tools, real-time monitoring, biopesticide development, and stronger regulatory frameworks. International cooperation, farmer education, and scientifically informed policies will be critical to future success. https://jsci.utq.edu.iq/index.php/main/article/view/1381insecticide resistanceagricultural pestsintegrated pest managementCRISPRRNA interference.
spellingShingle Ihsan Khudhair
Naseer Malaky Abbood
Yasser Ahmed Mahmoud El-Amier
Insecticide Resistance in Agricultural Pests: Mechanisms, Case Studies, and Future Directions
مجلة علوم ذي قار
insecticide resistance
agricultural pests
integrated pest management
CRISPR
RNA interference.
title Insecticide Resistance in Agricultural Pests: Mechanisms, Case Studies, and Future Directions
title_full Insecticide Resistance in Agricultural Pests: Mechanisms, Case Studies, and Future Directions
title_fullStr Insecticide Resistance in Agricultural Pests: Mechanisms, Case Studies, and Future Directions
title_full_unstemmed Insecticide Resistance in Agricultural Pests: Mechanisms, Case Studies, and Future Directions
title_short Insecticide Resistance in Agricultural Pests: Mechanisms, Case Studies, and Future Directions
title_sort insecticide resistance in agricultural pests mechanisms case studies and future directions
topic insecticide resistance
agricultural pests
integrated pest management
CRISPR
RNA interference.
url https://jsci.utq.edu.iq/index.php/main/article/view/1381
work_keys_str_mv AT ihsankhudhair insecticideresistanceinagriculturalpestsmechanismscasestudiesandfuturedirections
AT naseermalakyabbood insecticideresistanceinagriculturalpestsmechanismscasestudiesandfuturedirections
AT yasserahmedmahmoudelamier insecticideresistanceinagriculturalpestsmechanismscasestudiesandfuturedirections