Dissemination of clinical Escherichia coli harboring the mcr-1 gene in Pakistan

Dissemination of clinical Escherichia coli harboring the mcr-1 gene in Pakistan

BackgroundColistin is an antibiotic used as a last resort to treat multidrug-resistant Gram-negative bacterial infections. Plasmid-mediated mobile colistin-resistant (mcr) genes in Escherichia coli (E. coli) are disseminated globally and are considered to be a major public health threat. This study...

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Bibliographic Details
Main Authors: Sabahat Abdullah, Muhammad Ahmad Mushtaq, Kalim Ullah, Brekhna Hassan, Mariya Azam, Muhammad Asif Zahoor, Juan Wang, Jianzhen Xu, Mark A. Toleman, Mashkoor Mohsin
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Microbiology
Subjects:
Escherichia coli
Colistin
MCR-1
whole-genome sequencing
antibiotic resistance
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2024.1502528/full
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