Single-cell analysis reveals CD34+CD90+ endothelial cells promote tumor metastasis in gallbladder cancer

Single-cell analysis reveals CD34+CD90+ endothelial cells promote tumor metastasis in gallbladder cancer

Abstract Gallbladder cancer (GBC) is the most common malignancy of the biliary tract, with high metastasis incidence and extremely low survival rate. The tumor endothelial cells (TECs) are fundamental components in the tumor microenvironment and significantly contribute to various tumor progression;...

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Main Authors: Minghui Hou, Jianan Chen, Youhai Jiang, Chunliang Liu, Xiang Wang, Erdong Liu, Yali Zong, Mingye Gu, Zhengyuan Meng, Senyan Wang, Wenjuan Wei, Qi Liu, Hongyang Wang, Jing Fu, Xiaofang Zhao
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:npj Precision Oncology
Online Access:https://doi.org/10.1038/s41698-025-01040-2
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