Artificial intelligence based advancements in nanomedicine for brain disorder management: an updated narrative review

Nanomedicines are nanoscale, biocompatible materials that offer promising alternatives to conventional treatment options for brain disorders. The recent technological developments in artificial intelligence (AI), particularly machine learning (ML) and deep learning (DL), are transforming the nanomed...

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Main Authors: Pankaj Dipankar, Diego Salazar, Elizabeth Dennard, Shanid Mohiyuddin, Quynh C. Nguyen
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Medicine
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Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2025.1599340/full
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author Pankaj Dipankar
Diego Salazar
Elizabeth Dennard
Shanid Mohiyuddin
Quynh C. Nguyen
author_facet Pankaj Dipankar
Diego Salazar
Elizabeth Dennard
Shanid Mohiyuddin
Quynh C. Nguyen
author_sort Pankaj Dipankar
collection DOAJ
description Nanomedicines are nanoscale, biocompatible materials that offer promising alternatives to conventional treatment options for brain disorders. The recent technological developments in artificial intelligence (AI), particularly machine learning (ML) and deep learning (DL), are transforming the nanomedicine field by improving disease diagnosis, biomarker identification, prognostic assessment and disease monitoring, targeted drug delivery, and therapeutic intervention as well as contributing to computational and methodological developments. These advancements can be achieved by analysis of large clinical datasets and facilitating the design and optimization of nanomaterials for in vivo testing. Such advancement offers exciting possibilities for the improvement in the management of brain disorders, including brain cancer, Alzheimer’s disease, Parkinson’s disease, and multiple sclerosis, where early diagnosis, targeted delivery, and effective treatment strategies remain a great challenge. This review article provides an overview of recent advances in AI-based nanomedicine development to accelerate effective and quick diagnosis, biomarker identification, prognosis, drug delivery, methodological advancement and patient-specific therapies for managing brain disorders.
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spelling doaj-art-265b4e4cb3a044cbae74445d8887cac62025-08-20T02:57:36ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2025-05-011210.3389/fmed.2025.15993401599340Artificial intelligence based advancements in nanomedicine for brain disorder management: an updated narrative reviewPankaj Dipankar0Diego Salazar1Elizabeth Dennard2Shanid Mohiyuddin3Quynh C. Nguyen4National Institute of Nursing Research, National Institutes of Health, Bethesda, MD, United StatesNational Institute of Nursing Research, National Institutes of Health, Bethesda, MD, United StatesSchool of Public Health, Epidemiology and Biostatistics, University of Maryland, College Park, MD, United StatesDivision of Hematology and Medical Oncology, Department of Medicine, Ellis Fischel Cancer Center, University of Missouri, Columbia, MO, United StatesNational Institute of Nursing Research, National Institutes of Health, Bethesda, MD, United StatesNanomedicines are nanoscale, biocompatible materials that offer promising alternatives to conventional treatment options for brain disorders. The recent technological developments in artificial intelligence (AI), particularly machine learning (ML) and deep learning (DL), are transforming the nanomedicine field by improving disease diagnosis, biomarker identification, prognostic assessment and disease monitoring, targeted drug delivery, and therapeutic intervention as well as contributing to computational and methodological developments. These advancements can be achieved by analysis of large clinical datasets and facilitating the design and optimization of nanomaterials for in vivo testing. Such advancement offers exciting possibilities for the improvement in the management of brain disorders, including brain cancer, Alzheimer’s disease, Parkinson’s disease, and multiple sclerosis, where early diagnosis, targeted delivery, and effective treatment strategies remain a great challenge. This review article provides an overview of recent advances in AI-based nanomedicine development to accelerate effective and quick diagnosis, biomarker identification, prognosis, drug delivery, methodological advancement and patient-specific therapies for managing brain disorders.https://www.frontiersin.org/articles/10.3389/fmed.2025.1599340/fullartificial intelligencebrain disordersdeep learningnanomaterialmachine learningnanomedicine
spellingShingle Pankaj Dipankar
Diego Salazar
Elizabeth Dennard
Shanid Mohiyuddin
Quynh C. Nguyen
Artificial intelligence based advancements in nanomedicine for brain disorder management: an updated narrative review
Frontiers in Medicine
artificial intelligence
brain disorders
deep learning
nanomaterial
machine learning
nanomedicine
title Artificial intelligence based advancements in nanomedicine for brain disorder management: an updated narrative review
title_full Artificial intelligence based advancements in nanomedicine for brain disorder management: an updated narrative review
title_fullStr Artificial intelligence based advancements in nanomedicine for brain disorder management: an updated narrative review
title_full_unstemmed Artificial intelligence based advancements in nanomedicine for brain disorder management: an updated narrative review
title_short Artificial intelligence based advancements in nanomedicine for brain disorder management: an updated narrative review
title_sort artificial intelligence based advancements in nanomedicine for brain disorder management an updated narrative review
topic artificial intelligence
brain disorders
deep learning
nanomaterial
machine learning
nanomedicine
url https://www.frontiersin.org/articles/10.3389/fmed.2025.1599340/full
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