Disruption of Nrf2 Enhances Upregulation of Nuclear Factor-κB Activity, Proinflammatory Cytokines, and Intercellular Adhesion Molecule-1 in the Brain after Traumatic Brain Injury
Inflammatory response plays an important role in the pathogenesis of secondary brain injury after traumatic brain injury (TBI). Nuclear factor erythroid 2-related factor 2 (Nrf2) is a key transcription factor that plays a crucial role in cytoprotection against inflammation. The present study investi...
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| Main Authors: | Wei Jin, Handong Wang, Wei Yan, Lizhi Xu, Xiaoliang Wang, Xiaoning Zhao, Xiaohe Yang, Gang Chen, Yan Ji |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2008-01-01
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| Series: | Mediators of Inflammation |
| Online Access: | http://dx.doi.org/10.1155/2008/725174 |
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