Successful use of anifrolumab in refractory cutaneous lupus erythematosus with systemic lupus erythematosus: A case report

A 61-year-old female with systemic lupus erythematosus presented with refractory discoid lupus. Despite treatment with numerous immunosuppressive therapies, including prednisone, hydroxychloroquine and mycophenolate mofetil, her cutaneous lupus remained active and significantly impacted her quality...

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Main Authors: Abdullah Ramadhan, Anita Troung, Elaine Yacyshyn, Robert Gniadecki
Format: Article
Language:English
Published: SAGE Publishing 2025-06-01
Series:SAGE Open Medical Case Reports
Online Access:https://doi.org/10.1177/2050313X251350376
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author Abdullah Ramadhan
Anita Troung
Elaine Yacyshyn
Robert Gniadecki
author_facet Abdullah Ramadhan
Anita Troung
Elaine Yacyshyn
Robert Gniadecki
author_sort Abdullah Ramadhan
collection DOAJ
description A 61-year-old female with systemic lupus erythematosus presented with refractory discoid lupus. Despite treatment with numerous immunosuppressive therapies, including prednisone, hydroxychloroquine and mycophenolate mofetil, her cutaneous lupus remained active and significantly impacted her quality of life. Introduction of anifrolumab led to remarkable improvement, highlighting its potential for refractory discoid lupus erythematosus.
format Article
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institution Kabale University
issn 2050-313X
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publishDate 2025-06-01
publisher SAGE Publishing
record_format Article
series SAGE Open Medical Case Reports
spelling doaj-art-264f2a69ccd94ca189b6c90c43f4a7422025-08-20T03:50:26ZengSAGE PublishingSAGE Open Medical Case Reports2050-313X2025-06-011310.1177/2050313X251350376Successful use of anifrolumab in refractory cutaneous lupus erythematosus with systemic lupus erythematosus: A case reportAbdullah Ramadhan0Anita Troung1Elaine Yacyshyn2Robert Gniadecki3Department of Dermatology, University of Alberta, Edmonton, AB, CanadaDepartment of Dermatology, University of Alberta, Edmonton, AB, CanadaDepartment of Dermatology, University of Alberta, Edmonton, AB, CanadaDepartment of Dermatology, University of Alberta, Edmonton, AB, CanadaA 61-year-old female with systemic lupus erythematosus presented with refractory discoid lupus. Despite treatment with numerous immunosuppressive therapies, including prednisone, hydroxychloroquine and mycophenolate mofetil, her cutaneous lupus remained active and significantly impacted her quality of life. Introduction of anifrolumab led to remarkable improvement, highlighting its potential for refractory discoid lupus erythematosus.https://doi.org/10.1177/2050313X251350376
spellingShingle Abdullah Ramadhan
Anita Troung
Elaine Yacyshyn
Robert Gniadecki
Successful use of anifrolumab in refractory cutaneous lupus erythematosus with systemic lupus erythematosus: A case report
SAGE Open Medical Case Reports
title Successful use of anifrolumab in refractory cutaneous lupus erythematosus with systemic lupus erythematosus: A case report
title_full Successful use of anifrolumab in refractory cutaneous lupus erythematosus with systemic lupus erythematosus: A case report
title_fullStr Successful use of anifrolumab in refractory cutaneous lupus erythematosus with systemic lupus erythematosus: A case report
title_full_unstemmed Successful use of anifrolumab in refractory cutaneous lupus erythematosus with systemic lupus erythematosus: A case report
title_short Successful use of anifrolumab in refractory cutaneous lupus erythematosus with systemic lupus erythematosus: A case report
title_sort successful use of anifrolumab in refractory cutaneous lupus erythematosus with systemic lupus erythematosus a case report
url https://doi.org/10.1177/2050313X251350376
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AT anitatroung successfuluseofanifrolumabinrefractorycutaneouslupuserythematosuswithsystemiclupuserythematosusacasereport
AT elaineyacyshyn successfuluseofanifrolumabinrefractorycutaneouslupuserythematosuswithsystemiclupuserythematosusacasereport
AT robertgniadecki successfuluseofanifrolumabinrefractorycutaneouslupuserythematosuswithsystemiclupuserythematosusacasereport