Relationship between the atherogenic index of plasma and the prevalence of kidney stones: insights from a population-based cross-sectional study
Objective To investigate the association between atherogenic index of plasma (AIP) and kidney stones (KS) occurrence and recurrence.Methods Data were obtained from the National Health and Nutrition Examination Survey (NHANES) 2007–2014. Non-pregnant adults who provided complete information on AIP an...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2024-12-01
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| Series: | Renal Failure |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/0886022X.2024.2390566 |
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| author | Dawei Wang Feng Shi Dingguo Zhang Lin Zhang Hui Wang Zijian Zhou Yu Zhu |
| author_facet | Dawei Wang Feng Shi Dingguo Zhang Lin Zhang Hui Wang Zijian Zhou Yu Zhu |
| author_sort | Dawei Wang |
| collection | DOAJ |
| description | Objective To investigate the association between atherogenic index of plasma (AIP) and kidney stones (KS) occurrence and recurrence.Methods Data were obtained from the National Health and Nutrition Examination Survey (NHANES) 2007–2014. Non-pregnant adults who provided complete information on AIP and KS were included in the analyses. AIP was calculated as log (triglyceride/high-density lipoprotein cholesterol). KS was ascertained with questionnaires. Weighted multivariable logistic regression model and restricted cubic spline (RCS) were applied to examine the associations between AIP and KS occurrence and recurrence.Results A total of 6488 subjects (weighted mean age 43.19 years and 49.26% male) with a weighted mean AIP of 0.66 were included in this study. The multivariable-adjusted OR for nephrolithiasis occurrence across consecutive tertiles was 1.00 (reference), 1.21 (95% CI: 0.90–1.62), and 1.85 (95% CI: 1.39–2.48), respectively. Moreover, each SD increment of AIP was associated with a 50% (OR:1.50, 95% CI: 1.25–1.81) higher risk of nephrolithiasis recurrence. RCSs showed significant and linear dose-response relationships between AIP and nephrolithiasis occurrence (p-overall = 0.006, p-nonlinear = 0.689) and recurrence (p-overall = 0.001, p-nonlinear = 0.848). The positive associations between AIP and nephrolithiasis occurrence and recurrence persisted in sensitivity analyses, suggesting the robustness of the results.Conclusion In the current US nationally representative cross-sectional study, AIP was positively associated with KS occurrence and recurrence. |
| format | Article |
| id | doaj-art-263e211ab7fe48e4a46c033ef13e3e21 |
| institution | OA Journals |
| issn | 0886-022X 1525-6049 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Renal Failure |
| spelling | doaj-art-263e211ab7fe48e4a46c033ef13e3e212025-08-20T02:29:58ZengTaylor & Francis GroupRenal Failure0886-022X1525-60492024-12-0146210.1080/0886022X.2024.2390566Relationship between the atherogenic index of plasma and the prevalence of kidney stones: insights from a population-based cross-sectional studyDawei Wang0Feng Shi1Dingguo Zhang2Lin Zhang3Hui Wang4Zijian Zhou5Yu Zhu6Department of Urology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, ChinaCAAC East China Aviation Personnel Medical Appraisal Center, Civil Aviation Shanghai Hospital, Shanghai, ChinaDepartment of Urology, Shanghai Pudong New Area People’s Hospital, Shanghai, ChinaThe School of Public Health and Preventive Medicine, Monash University, AustraliaDepartment of Urology, Shanghai Anting Hospital, Shanghai, ChinaDepartment of Urology, Huashan Hospital, Fudan University, Shanghai, ChinaDepartment of Urology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, ChinaObjective To investigate the association between atherogenic index of plasma (AIP) and kidney stones (KS) occurrence and recurrence.Methods Data were obtained from the National Health and Nutrition Examination Survey (NHANES) 2007–2014. Non-pregnant adults who provided complete information on AIP and KS were included in the analyses. AIP was calculated as log (triglyceride/high-density lipoprotein cholesterol). KS was ascertained with questionnaires. Weighted multivariable logistic regression model and restricted cubic spline (RCS) were applied to examine the associations between AIP and KS occurrence and recurrence.Results A total of 6488 subjects (weighted mean age 43.19 years and 49.26% male) with a weighted mean AIP of 0.66 were included in this study. The multivariable-adjusted OR for nephrolithiasis occurrence across consecutive tertiles was 1.00 (reference), 1.21 (95% CI: 0.90–1.62), and 1.85 (95% CI: 1.39–2.48), respectively. Moreover, each SD increment of AIP was associated with a 50% (OR:1.50, 95% CI: 1.25–1.81) higher risk of nephrolithiasis recurrence. RCSs showed significant and linear dose-response relationships between AIP and nephrolithiasis occurrence (p-overall = 0.006, p-nonlinear = 0.689) and recurrence (p-overall = 0.001, p-nonlinear = 0.848). The positive associations between AIP and nephrolithiasis occurrence and recurrence persisted in sensitivity analyses, suggesting the robustness of the results.Conclusion In the current US nationally representative cross-sectional study, AIP was positively associated with KS occurrence and recurrence.https://www.tandfonline.com/doi/10.1080/0886022X.2024.2390566Kidney stoneatherogenic index of plasmaNHANEScross-sectional studydyslipidemia |
| spellingShingle | Dawei Wang Feng Shi Dingguo Zhang Lin Zhang Hui Wang Zijian Zhou Yu Zhu Relationship between the atherogenic index of plasma and the prevalence of kidney stones: insights from a population-based cross-sectional study Renal Failure Kidney stone atherogenic index of plasma NHANES cross-sectional study dyslipidemia |
| title | Relationship between the atherogenic index of plasma and the prevalence of kidney stones: insights from a population-based cross-sectional study |
| title_full | Relationship between the atherogenic index of plasma and the prevalence of kidney stones: insights from a population-based cross-sectional study |
| title_fullStr | Relationship between the atherogenic index of plasma and the prevalence of kidney stones: insights from a population-based cross-sectional study |
| title_full_unstemmed | Relationship between the atherogenic index of plasma and the prevalence of kidney stones: insights from a population-based cross-sectional study |
| title_short | Relationship between the atherogenic index of plasma and the prevalence of kidney stones: insights from a population-based cross-sectional study |
| title_sort | relationship between the atherogenic index of plasma and the prevalence of kidney stones insights from a population based cross sectional study |
| topic | Kidney stone atherogenic index of plasma NHANES cross-sectional study dyslipidemia |
| url | https://www.tandfonline.com/doi/10.1080/0886022X.2024.2390566 |
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