Role of autoreactive Tc17 cells in the pathogenesis of experimental autoimmune encephalomyelitis

Role of autoreactive Tc17 cells in the pathogenesis of experimental autoimmune encephalomyelitis

Abstract Background The pathogenesis of multiple sclerosis (MS) and experimental autoimmune encephalomyelitis (EAE—an animal model of MS) is primarily mediated by T cells. However, recent studies have only focused on interleukin (IL)‐17‐secreting CD4+ T‐helper cells, also known as Th17 cells. This s...

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Bibliographic Details
Main Authors: Yong Peng, Xiuli Zhang, Yandan Tang, Shunqing He, Guilan Rao, Quan Chen, Yahui Xue, Hong Jin, Shu Liu, Ziyang Zhou, Yun Xiang
Format: Article
Language:English
Published: Wiley 2024-03-01
Series:Neuroprotection
Subjects:
CD8+ T cells
experimental autoimmune myelitis
IFN‐ γ
IL‐17
multiple sclerosis
Tc17 cells
Online Access:https://doi.org/10.1002/nep3.38
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