CONNECT Platform to Increase Diverse Engagement and Enrollment in Cardiovascular Clinical Research: Rationale, Design, and Lessons Learned in Early Implementation
Background Women and Black and Latino adults face a high burden of cardiovascular disease (CVD), yet remain underrepresented in CVD research. CONNECT (Developing a Learning Community to Increase Engagement and Enrollment in Cardiovascular Clinical Trials) is a participant‐centered learning platform...
Saved in:
| Main Authors: | , , , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2025-08-01
|
| Series: | Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease |
| Subjects: | |
| Online Access: | https://www.ahajournals.org/doi/10.1161/JAHA.124.038351 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849233308145156096 |
|---|---|
| author | Hailey N. Miller Erin Wong Samuel Byiringiro Zaib Hussain Monica Guerrero Vazquez Cassie Lewis‐Land Bianca Skelton Samantha Curriero Adriana Foster Foujan Moghimi Oluwatosin Tomiwa John Shaia Payam Sheikhattari Nae‐Yuh Wang Cheryl R. Dennison Himmelfarb |
| author_facet | Hailey N. Miller Erin Wong Samuel Byiringiro Zaib Hussain Monica Guerrero Vazquez Cassie Lewis‐Land Bianca Skelton Samantha Curriero Adriana Foster Foujan Moghimi Oluwatosin Tomiwa John Shaia Payam Sheikhattari Nae‐Yuh Wang Cheryl R. Dennison Himmelfarb |
| author_sort | Hailey N. Miller |
| collection | DOAJ |
| description | Background Women and Black and Latino adults face a high burden of cardiovascular disease (CVD), yet remain underrepresented in CVD research. CONNECT (Developing a Learning Community to Increase Engagement and Enrollment in Cardiovascular Clinical Trials) is a participant‐centered learning platform designed to (1) evaluate electronic health record‐informed and community‐engaged recruitment; (2) increase enrollment in CVD research; and (3) increase trust in and awareness of CVD research among 3 priority populations: women and Black and Latino adults. This article describes the rationale, design, and early implementation lessons. Methods CONNECT uses community‐engaged and digital approaches to recruit and engage women and Black and Latino adults, aiming to enroll 1000 participants. Participants receive 12 months of tailored heart health and research text messages and are connected to CVD research that aligns with their interests. The primary outcome is the proportion of individuals enrolled, by recruitment method and priority population. Other outcomes include proportion of participants who enroll in a CVD study and changes in awareness of and trust in research. CONNECT was codeveloped with a Community Research Council, a group of community consultants, and approved by local institutional review boards. Results Development and early implementation identified strategies for successful community partnerships, cross‐institutional collaboration, efficient technology infrastructures, tailored education materials, and researcher engagement. Conclusions CONNECT shows potential to address barriers to research participation, strengthen engagement and recruitment science, and improve diverse research participation. Findings from CONNECT will inform best practices to engage women and Black and Latino adults in CVD research. Registration URL: https://www.clinicaltrials.gov; Unique identifier: NCT06347484. |
| format | Article |
| id | doaj-art-26311767209c4f15afb5bfe88fa5d5b5 |
| institution | Kabale University |
| issn | 2047-9980 |
| language | English |
| publishDate | 2025-08-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease |
| spelling | doaj-art-26311767209c4f15afb5bfe88fa5d5b52025-08-20T07:24:54ZengWileyJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease2047-99802025-08-01141610.1161/JAHA.124.038351CONNECT Platform to Increase Diverse Engagement and Enrollment in Cardiovascular Clinical Research: Rationale, Design, and Lessons Learned in Early ImplementationHailey N. Miller0Erin Wong1Samuel Byiringiro2Zaib Hussain3Monica Guerrero Vazquez4Cassie Lewis‐Land5Bianca Skelton6Samantha Curriero7Adriana Foster8Foujan Moghimi9Oluwatosin Tomiwa10John Shaia11Payam Sheikhattari12Nae‐Yuh Wang13Cheryl R. Dennison Himmelfarb14School of Nursing Johns Hopkins University Baltimore MD USASchool of Nursing Johns Hopkins University Baltimore MD USASchool of Nursing Johns Hopkins University Baltimore MD USASchool of Medicine Johns Hopkins University Baltimore MD USASchool of Medicine Johns Hopkins University Baltimore MD USAInstitute for Clinical and Translational Research, Johns Hopkins University Baltimore MD USABloomberg School of Public Health Johns Hopkins University Baltimore MD USASchool of Nursing Johns Hopkins University Baltimore MD USAMorgan CARES Morgan State University Baltimore MD USASchool of Nursing Johns Hopkins University Baltimore MD USASchool of Nursing Johns Hopkins University Baltimore MD USABanner Neighborhoods Baltimore MD USASchool of Community Health & Policy Morgan State University Baltimore MD USAInstitute for Clinical and Translational Research, Johns Hopkins University Baltimore MD USASchool of Nursing Johns Hopkins University Baltimore MD USABackground Women and Black and Latino adults face a high burden of cardiovascular disease (CVD), yet remain underrepresented in CVD research. CONNECT (Developing a Learning Community to Increase Engagement and Enrollment in Cardiovascular Clinical Trials) is a participant‐centered learning platform designed to (1) evaluate electronic health record‐informed and community‐engaged recruitment; (2) increase enrollment in CVD research; and (3) increase trust in and awareness of CVD research among 3 priority populations: women and Black and Latino adults. This article describes the rationale, design, and early implementation lessons. Methods CONNECT uses community‐engaged and digital approaches to recruit and engage women and Black and Latino adults, aiming to enroll 1000 participants. Participants receive 12 months of tailored heart health and research text messages and are connected to CVD research that aligns with their interests. The primary outcome is the proportion of individuals enrolled, by recruitment method and priority population. Other outcomes include proportion of participants who enroll in a CVD study and changes in awareness of and trust in research. CONNECT was codeveloped with a Community Research Council, a group of community consultants, and approved by local institutional review boards. Results Development and early implementation identified strategies for successful community partnerships, cross‐institutional collaboration, efficient technology infrastructures, tailored education materials, and researcher engagement. Conclusions CONNECT shows potential to address barriers to research participation, strengthen engagement and recruitment science, and improve diverse research participation. Findings from CONNECT will inform best practices to engage women and Black and Latino adults in CVD research. Registration URL: https://www.clinicaltrials.gov; Unique identifier: NCT06347484.https://www.ahajournals.org/doi/10.1161/JAHA.124.038351cardiovascular diseasecardiovascular health promotioncommunity engagementdiversityelectronic health recordrecruitment |
| spellingShingle | Hailey N. Miller Erin Wong Samuel Byiringiro Zaib Hussain Monica Guerrero Vazquez Cassie Lewis‐Land Bianca Skelton Samantha Curriero Adriana Foster Foujan Moghimi Oluwatosin Tomiwa John Shaia Payam Sheikhattari Nae‐Yuh Wang Cheryl R. Dennison Himmelfarb CONNECT Platform to Increase Diverse Engagement and Enrollment in Cardiovascular Clinical Research: Rationale, Design, and Lessons Learned in Early Implementation Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease cardiovascular disease cardiovascular health promotion community engagement diversity electronic health record recruitment |
| title | CONNECT Platform to Increase Diverse Engagement and Enrollment in Cardiovascular Clinical Research: Rationale, Design, and Lessons Learned in Early Implementation |
| title_full | CONNECT Platform to Increase Diverse Engagement and Enrollment in Cardiovascular Clinical Research: Rationale, Design, and Lessons Learned in Early Implementation |
| title_fullStr | CONNECT Platform to Increase Diverse Engagement and Enrollment in Cardiovascular Clinical Research: Rationale, Design, and Lessons Learned in Early Implementation |
| title_full_unstemmed | CONNECT Platform to Increase Diverse Engagement and Enrollment in Cardiovascular Clinical Research: Rationale, Design, and Lessons Learned in Early Implementation |
| title_short | CONNECT Platform to Increase Diverse Engagement and Enrollment in Cardiovascular Clinical Research: Rationale, Design, and Lessons Learned in Early Implementation |
| title_sort | connect platform to increase diverse engagement and enrollment in cardiovascular clinical research rationale design and lessons learned in early implementation |
| topic | cardiovascular disease cardiovascular health promotion community engagement diversity electronic health record recruitment |
| url | https://www.ahajournals.org/doi/10.1161/JAHA.124.038351 |
| work_keys_str_mv | AT haileynmiller connectplatformtoincreasediverseengagementandenrollmentincardiovascularclinicalresearchrationaledesignandlessonslearnedinearlyimplementation AT erinwong connectplatformtoincreasediverseengagementandenrollmentincardiovascularclinicalresearchrationaledesignandlessonslearnedinearlyimplementation AT samuelbyiringiro connectplatformtoincreasediverseengagementandenrollmentincardiovascularclinicalresearchrationaledesignandlessonslearnedinearlyimplementation AT zaibhussain connectplatformtoincreasediverseengagementandenrollmentincardiovascularclinicalresearchrationaledesignandlessonslearnedinearlyimplementation AT monicaguerrerovazquez connectplatformtoincreasediverseengagementandenrollmentincardiovascularclinicalresearchrationaledesignandlessonslearnedinearlyimplementation AT cassielewisland connectplatformtoincreasediverseengagementandenrollmentincardiovascularclinicalresearchrationaledesignandlessonslearnedinearlyimplementation AT biancaskelton connectplatformtoincreasediverseengagementandenrollmentincardiovascularclinicalresearchrationaledesignandlessonslearnedinearlyimplementation AT samanthacurriero connectplatformtoincreasediverseengagementandenrollmentincardiovascularclinicalresearchrationaledesignandlessonslearnedinearlyimplementation AT adrianafoster connectplatformtoincreasediverseengagementandenrollmentincardiovascularclinicalresearchrationaledesignandlessonslearnedinearlyimplementation AT foujanmoghimi connectplatformtoincreasediverseengagementandenrollmentincardiovascularclinicalresearchrationaledesignandlessonslearnedinearlyimplementation AT oluwatosintomiwa connectplatformtoincreasediverseengagementandenrollmentincardiovascularclinicalresearchrationaledesignandlessonslearnedinearlyimplementation AT johnshaia connectplatformtoincreasediverseengagementandenrollmentincardiovascularclinicalresearchrationaledesignandlessonslearnedinearlyimplementation AT payamsheikhattari connectplatformtoincreasediverseengagementandenrollmentincardiovascularclinicalresearchrationaledesignandlessonslearnedinearlyimplementation AT naeyuhwang connectplatformtoincreasediverseengagementandenrollmentincardiovascularclinicalresearchrationaledesignandlessonslearnedinearlyimplementation AT cherylrdennisonhimmelfarb connectplatformtoincreasediverseengagementandenrollmentincardiovascularclinicalresearchrationaledesignandlessonslearnedinearlyimplementation |