A Case of Chronic Granulomatous Pancreatitis
We present a 23-year-old woman with a 4-year history of an ambiguous, nonmalignant pancreatic head mass and recurrent nausea/vomiting, right upper quadrant abdominal pain, jaundice, oral feeding intolerance, chronic portal vein thrombosis, and pancytopenia. A multidisciplinary effort with extensive...
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| Format: | Article |
| Language: | English |
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American College of Physicians
2025-06-01
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| Series: | Annals of Internal Medicine: Clinical Cases |
| Online Access: | https://www.acpjournals.org/doi/10.7326/aimcc.2025.0049 |
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| author | Ethan Angle Frida Teran-Garza Alex Paschke Bradley Manning |
| author_facet | Ethan Angle Frida Teran-Garza Alex Paschke Bradley Manning |
| author_sort | Ethan Angle |
| collection | DOAJ |
| description | We present a 23-year-old woman with a 4-year history of an ambiguous, nonmalignant pancreatic head mass and recurrent nausea/vomiting, right upper quadrant abdominal pain, jaundice, oral feeding intolerance, chronic portal vein thrombosis, and pancytopenia. A multidisciplinary effort with extensive history-taking, laboratory work-up, and repeated endoscopic ultrasound with fine-needle aspiration narrowed her differential diagnosis—which included IgG4-related disease—into the seventh instance of chronic granulomatous pancreatitis secondary to histoplasmosis that has been reported in the literature to our knowledge. The patient remains symptom free on her year-long course of itraconazole, and her satisfactory outcome is an exemplification of the diagnostic and therapeutic power in specialty consultation by hospitalists. |
| format | Article |
| id | doaj-art-262d8fd95ef149c3a9ef40a04376cb16 |
| institution | DOAJ |
| issn | 2767-7664 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | American College of Physicians |
| record_format | Article |
| series | Annals of Internal Medicine: Clinical Cases |
| spelling | doaj-art-262d8fd95ef149c3a9ef40a04376cb162025-08-20T03:19:20ZengAmerican College of PhysiciansAnnals of Internal Medicine: Clinical Cases2767-76642025-06-014610.7326/aimcc.2025.0049A Case of Chronic Granulomatous PancreatitisEthan Angle0Frida Teran-Garza1Alex Paschke2Bradley Manning31Carver College of Medicine, University of Iowa, Iowa City, Iowa2Department of Internal Medicine, University of Iowa Health Care Medical Center, Iowa City, Iowa2Department of Internal Medicine, University of Iowa Health Care Medical Center, Iowa City, Iowa2Department of Internal Medicine, University of Iowa Health Care Medical Center, Iowa City, IowaWe present a 23-year-old woman with a 4-year history of an ambiguous, nonmalignant pancreatic head mass and recurrent nausea/vomiting, right upper quadrant abdominal pain, jaundice, oral feeding intolerance, chronic portal vein thrombosis, and pancytopenia. A multidisciplinary effort with extensive history-taking, laboratory work-up, and repeated endoscopic ultrasound with fine-needle aspiration narrowed her differential diagnosis—which included IgG4-related disease—into the seventh instance of chronic granulomatous pancreatitis secondary to histoplasmosis that has been reported in the literature to our knowledge. The patient remains symptom free on her year-long course of itraconazole, and her satisfactory outcome is an exemplification of the diagnostic and therapeutic power in specialty consultation by hospitalists.https://www.acpjournals.org/doi/10.7326/aimcc.2025.0049 |
| spellingShingle | Ethan Angle Frida Teran-Garza Alex Paschke Bradley Manning A Case of Chronic Granulomatous Pancreatitis Annals of Internal Medicine: Clinical Cases |
| title | A Case of Chronic Granulomatous Pancreatitis |
| title_full | A Case of Chronic Granulomatous Pancreatitis |
| title_fullStr | A Case of Chronic Granulomatous Pancreatitis |
| title_full_unstemmed | A Case of Chronic Granulomatous Pancreatitis |
| title_short | A Case of Chronic Granulomatous Pancreatitis |
| title_sort | case of chronic granulomatous pancreatitis |
| url | https://www.acpjournals.org/doi/10.7326/aimcc.2025.0049 |
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