Critical Appraisal of Clinical Practice Guidelines for Age-Related Macular Degeneration

Purpose. To evaluate the methodological quality of age-related macular degeneration (AMD) clinical practice guidelines (CPGs). Methods. AMD CPGs published by the American Academy of Ophthalmology (AAO) and Royal College of Ophthalmologists (RCO) were appraised by independent reviewers using the Appr...

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Main Authors: Annie M. Wu, Connie M. Wu, Benjamin K. Young, Dominic J. Wu, Curtis E. Margo, Paul B. Greenberg
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Journal of Ophthalmology
Online Access:http://dx.doi.org/10.1155/2015/710324
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author Annie M. Wu
Connie M. Wu
Benjamin K. Young
Dominic J. Wu
Curtis E. Margo
Paul B. Greenberg
author_facet Annie M. Wu
Connie M. Wu
Benjamin K. Young
Dominic J. Wu
Curtis E. Margo
Paul B. Greenberg
author_sort Annie M. Wu
collection DOAJ
description Purpose. To evaluate the methodological quality of age-related macular degeneration (AMD) clinical practice guidelines (CPGs). Methods. AMD CPGs published by the American Academy of Ophthalmology (AAO) and Royal College of Ophthalmologists (RCO) were appraised by independent reviewers using the Appraisal of Guidelines for Research and Evaluation (AGREE) II instrument, which comprises six domains (Scope and Purpose, Stakeholder Involvement, Rigor of Development, Clarity of Presentation, Applicability, and Editorial Independence), and an Overall Assessment score summarizing methodological quality across all domains. Results. Average domain scores ranged from 35% to 83% for the AAO CPG and from 17% to 83% for the RCO CPG. Intraclass correlation coefficients for the reliability of mean scores for the AAO and RCO CPGs were 0.74 and 0.88, respectively. The strongest domains were Scope and Purpose and Clarity of Presentation. The weakest were Stakeholder Involvement (AAO) and Editorial Independence (RCO). Conclusions. Future AMD CPGs can be improved by involving all relevant stakeholders in guideline development, ensuring transparency of guideline development and review methodology, improving guideline applicability with respect to economic considerations, and addressing potential conflict of interests within the development group.
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spelling doaj-art-26253c835ab64a71b0889855e3ca20562025-02-03T06:12:56ZengWileyJournal of Ophthalmology2090-004X2090-00582015-01-01201510.1155/2015/710324710324Critical Appraisal of Clinical Practice Guidelines for Age-Related Macular DegenerationAnnie M. Wu0Connie M. Wu1Benjamin K. Young2Dominic J. Wu3Curtis E. Margo4Paul B. Greenberg5Section of Ophthalmology, Providence VA Medical Center, Providence, RI 02908, USASection of Ophthalmology, Providence VA Medical Center, Providence, RI 02908, USASection of Ophthalmology, Providence VA Medical Center, Providence, RI 02908, USASection of Ophthalmology, Providence VA Medical Center, Providence, RI 02908, USADepartments of Ophthalmology, Pathology and Cell Biology, Morsani College of Medicine, Tampa, FL 33612, USASection of Ophthalmology, Providence VA Medical Center, Providence, RI 02908, USAPurpose. To evaluate the methodological quality of age-related macular degeneration (AMD) clinical practice guidelines (CPGs). Methods. AMD CPGs published by the American Academy of Ophthalmology (AAO) and Royal College of Ophthalmologists (RCO) were appraised by independent reviewers using the Appraisal of Guidelines for Research and Evaluation (AGREE) II instrument, which comprises six domains (Scope and Purpose, Stakeholder Involvement, Rigor of Development, Clarity of Presentation, Applicability, and Editorial Independence), and an Overall Assessment score summarizing methodological quality across all domains. Results. Average domain scores ranged from 35% to 83% for the AAO CPG and from 17% to 83% for the RCO CPG. Intraclass correlation coefficients for the reliability of mean scores for the AAO and RCO CPGs were 0.74 and 0.88, respectively. The strongest domains were Scope and Purpose and Clarity of Presentation. The weakest were Stakeholder Involvement (AAO) and Editorial Independence (RCO). Conclusions. Future AMD CPGs can be improved by involving all relevant stakeholders in guideline development, ensuring transparency of guideline development and review methodology, improving guideline applicability with respect to economic considerations, and addressing potential conflict of interests within the development group.http://dx.doi.org/10.1155/2015/710324
spellingShingle Annie M. Wu
Connie M. Wu
Benjamin K. Young
Dominic J. Wu
Curtis E. Margo
Paul B. Greenberg
Critical Appraisal of Clinical Practice Guidelines for Age-Related Macular Degeneration
Journal of Ophthalmology
title Critical Appraisal of Clinical Practice Guidelines for Age-Related Macular Degeneration
title_full Critical Appraisal of Clinical Practice Guidelines for Age-Related Macular Degeneration
title_fullStr Critical Appraisal of Clinical Practice Guidelines for Age-Related Macular Degeneration
title_full_unstemmed Critical Appraisal of Clinical Practice Guidelines for Age-Related Macular Degeneration
title_short Critical Appraisal of Clinical Practice Guidelines for Age-Related Macular Degeneration
title_sort critical appraisal of clinical practice guidelines for age related macular degeneration
url http://dx.doi.org/10.1155/2015/710324
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