The Use of AgNP-Containing Nanocomposites Based on Galactomannan and κ-Carrageenan for the Creation of Hydrogels with Antiradical Activity
Series of composites containing 2.5–17.0% Ag and consisting of spherical silver nanoparticles with sizes ranging from 5.1 to 18.3 nm and from 6.4 to 21.8 nm for GM- and κ-CG-based composites, respectively, were prepared using the reducing and stabilizing ability of the natural polysaccharides galact...
Saved in:
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2024-12-01
|
| Series: | Gels |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2310-2861/10/12/800 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850240811289018368 |
|---|---|
| author | Marina Zvereva |
| author_facet | Marina Zvereva |
| author_sort | Marina Zvereva |
| collection | DOAJ |
| description | Series of composites containing 2.5–17.0% Ag and consisting of spherical silver nanoparticles with sizes ranging from 5.1 to 18.3 nm and from 6.4 to 21.8 nm for GM- and κ-CG-based composites, respectively, were prepared using the reducing and stabilizing ability of the natural polysaccharides galactomannan (GM) and κ-carrageenan (κ-CG). The antiradical activity of the obtained composites was evaluated using the decolorization of ABTS+<sup>·</sup> solution. It was found that the IC<sub>50</sub> value of a composite’s aqueous solution depends on the type of stabilizing ligand, the amount of inorganic phases, and the average size of AgNPs, and varies in the range of 0.015–0.08 mg·mL<sup>−1</sup> and 0.03–0.59 mg·mL<sup>−1</sup> for GM-AgNPs − κ-CG-AgNPs composites, respectively. GM-AgNPs − κ-CG-AgNPs hydrogels were successfully prepared and characterized on the basis of composites containing 2.5% Ag (demonstrating the most pronounced antiradical activity in terms of IC<sub>50</sub> values per mole amount of Ag). It was found that the optimal ratio of composites that provided the best water-holding capacity and prolonged complete release of AgNPs from the hydrogel composition was 1:1. The influence of Ca<sup>2+</sup> cations on the co-gel formation of the GM-AgNPs − κ-CG-AgNPs system, as well as the expression of their water-holding capacity and the rate of AgNPs release from the hydrogel carrier, was evaluated. |
| format | Article |
| id | doaj-art-26206bf3e9e8443c92780ebc92013d1b |
| institution | OA Journals |
| issn | 2310-2861 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Gels |
| spelling | doaj-art-26206bf3e9e8443c92780ebc92013d1b2025-08-20T02:00:46ZengMDPI AGGels2310-28612024-12-01101280010.3390/gels10120800The Use of AgNP-Containing Nanocomposites Based on Galactomannan and κ-Carrageenan for the Creation of Hydrogels with Antiradical ActivityMarina Zvereva0A.E. Favorsky Irkutsk Institute of Chemistry, 664033 Irkutsk, RussiaSeries of composites containing 2.5–17.0% Ag and consisting of spherical silver nanoparticles with sizes ranging from 5.1 to 18.3 nm and from 6.4 to 21.8 nm for GM- and κ-CG-based composites, respectively, were prepared using the reducing and stabilizing ability of the natural polysaccharides galactomannan (GM) and κ-carrageenan (κ-CG). The antiradical activity of the obtained composites was evaluated using the decolorization of ABTS+<sup>·</sup> solution. It was found that the IC<sub>50</sub> value of a composite’s aqueous solution depends on the type of stabilizing ligand, the amount of inorganic phases, and the average size of AgNPs, and varies in the range of 0.015–0.08 mg·mL<sup>−1</sup> and 0.03–0.59 mg·mL<sup>−1</sup> for GM-AgNPs − κ-CG-AgNPs composites, respectively. GM-AgNPs − κ-CG-AgNPs hydrogels were successfully prepared and characterized on the basis of composites containing 2.5% Ag (demonstrating the most pronounced antiradical activity in terms of IC<sub>50</sub> values per mole amount of Ag). It was found that the optimal ratio of composites that provided the best water-holding capacity and prolonged complete release of AgNPs from the hydrogel composition was 1:1. The influence of Ca<sup>2+</sup> cations on the co-gel formation of the GM-AgNPs − κ-CG-AgNPs system, as well as the expression of their water-holding capacity and the rate of AgNPs release from the hydrogel carrier, was evaluated.https://www.mdpi.com/2310-2861/10/12/800hydrogelscarrageenangalactomannansilver nanoparticlesantiradical activity |
| spellingShingle | Marina Zvereva The Use of AgNP-Containing Nanocomposites Based on Galactomannan and κ-Carrageenan for the Creation of Hydrogels with Antiradical Activity Gels hydrogels carrageenan galactomannan silver nanoparticles antiradical activity |
| title | The Use of AgNP-Containing Nanocomposites Based on Galactomannan and κ-Carrageenan for the Creation of Hydrogels with Antiradical Activity |
| title_full | The Use of AgNP-Containing Nanocomposites Based on Galactomannan and κ-Carrageenan for the Creation of Hydrogels with Antiradical Activity |
| title_fullStr | The Use of AgNP-Containing Nanocomposites Based on Galactomannan and κ-Carrageenan for the Creation of Hydrogels with Antiradical Activity |
| title_full_unstemmed | The Use of AgNP-Containing Nanocomposites Based on Galactomannan and κ-Carrageenan for the Creation of Hydrogels with Antiradical Activity |
| title_short | The Use of AgNP-Containing Nanocomposites Based on Galactomannan and κ-Carrageenan for the Creation of Hydrogels with Antiradical Activity |
| title_sort | use of agnp containing nanocomposites based on galactomannan and κ carrageenan for the creation of hydrogels with antiradical activity |
| topic | hydrogels carrageenan galactomannan silver nanoparticles antiradical activity |
| url | https://www.mdpi.com/2310-2861/10/12/800 |
| work_keys_str_mv | AT marinazvereva theuseofagnpcontainingnanocompositesbasedongalactomannanandkcarrageenanforthecreationofhydrogelswithantiradicalactivity AT marinazvereva useofagnpcontainingnanocompositesbasedongalactomannanandkcarrageenanforthecreationofhydrogelswithantiradicalactivity |