Transmission potential of African, Asian and American Zika virus strains by Aedes aegypti and Culex quinquefasciatus from Guadeloupe (French West Indies)

Zika virus (ZIKV) is an arbovirus that has dramatically spread in South America and the Caribbean regions since 2015. The majority of vector incrimination studies available for ZIKV showed that Aedes aegypti mosquitoes are important vectors for this virus. However, several reports suggest that Culex...

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Main Authors: Lyza Hery, Antoine Boullis, Christelle Delannay, Anubis Vega-Rúa
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:Emerging Microbes and Infections
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Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2019.1615849
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author Lyza Hery
Antoine Boullis
Christelle Delannay
Anubis Vega-Rúa
author_facet Lyza Hery
Antoine Boullis
Christelle Delannay
Anubis Vega-Rúa
author_sort Lyza Hery
collection DOAJ
description Zika virus (ZIKV) is an arbovirus that has dramatically spread in South America and the Caribbean regions since 2015. The majority of vector incrimination studies available for ZIKV showed that Aedes aegypti mosquitoes are important vectors for this virus. However, several reports suggest that Culex quinquefasciatus mosquitoes may be implicated in ZIKV transmission in certain urban settings. In the present study, we evaluated the vector competence for ZIKV of Cx. quinquefasciatus and Ae. aegypti mosquitoes from Guadeloupe using African, American and Asian strains. The results demonstrated that Cx. quinquefasciatus is refractory to ZIKV infection whatever the strain tested at 7, 14 or 21 days post-infection (dpi), while ZIKV transmission was recorded in Ae. aegypti for all the three strains. The African ZIKV strain was better transmitted by Ae. aegypti (∼ 50% mean transmission efficiency) and with a shorter incubation period (7 dpi) when compared to the Asian and American strains (<14% transmission efficiency; incubation period of 14–21 dpi). Taken together, these results suggest that only Ae. aegypti mosquitoes are involved in urban ZIKV transmission in Guadeloupe and highlight a higher infectiousness of the African ZIKV strain in this mosquito species when compared to the Asian and American ones.
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spelling doaj-art-261cc2e0d70e4949bbc478cfe42cbdec2025-08-20T03:17:35ZengTaylor & Francis GroupEmerging Microbes and Infections2222-17512019-01-018169970610.1080/22221751.2019.1615849Transmission potential of African, Asian and American Zika virus strains by Aedes aegypti and Culex quinquefasciatus from Guadeloupe (French West Indies)Lyza Hery0Antoine Boullis1Christelle Delannay2Anubis Vega-Rúa3Institute Pasteur of Guadeloupe, Laboratory of Vector Control research, Unit Transmission Reservoir and Pathogens Diversity, Les Abymes, FranceInstitute Pasteur of Guadeloupe, Laboratory of Vector Control research, Unit Transmission Reservoir and Pathogens Diversity, Les Abymes, FranceInstitute Pasteur of Guadeloupe, Laboratory of Vector Control research, Unit Transmission Reservoir and Pathogens Diversity, Les Abymes, FranceInstitute Pasteur of Guadeloupe, Laboratory of Vector Control research, Unit Transmission Reservoir and Pathogens Diversity, Les Abymes, FranceZika virus (ZIKV) is an arbovirus that has dramatically spread in South America and the Caribbean regions since 2015. The majority of vector incrimination studies available for ZIKV showed that Aedes aegypti mosquitoes are important vectors for this virus. However, several reports suggest that Culex quinquefasciatus mosquitoes may be implicated in ZIKV transmission in certain urban settings. In the present study, we evaluated the vector competence for ZIKV of Cx. quinquefasciatus and Ae. aegypti mosquitoes from Guadeloupe using African, American and Asian strains. The results demonstrated that Cx. quinquefasciatus is refractory to ZIKV infection whatever the strain tested at 7, 14 or 21 days post-infection (dpi), while ZIKV transmission was recorded in Ae. aegypti for all the three strains. The African ZIKV strain was better transmitted by Ae. aegypti (∼ 50% mean transmission efficiency) and with a shorter incubation period (7 dpi) when compared to the Asian and American strains (<14% transmission efficiency; incubation period of 14–21 dpi). Taken together, these results suggest that only Ae. aegypti mosquitoes are involved in urban ZIKV transmission in Guadeloupe and highlight a higher infectiousness of the African ZIKV strain in this mosquito species when compared to the Asian and American ones.https://www.tandfonline.com/doi/10.1080/22221751.2019.1615849Aedes aegyptiCulex quinquefasciatusZika virusGuadeloupevector competence
spellingShingle Lyza Hery
Antoine Boullis
Christelle Delannay
Anubis Vega-Rúa
Transmission potential of African, Asian and American Zika virus strains by Aedes aegypti and Culex quinquefasciatus from Guadeloupe (French West Indies)
Emerging Microbes and Infections
Aedes aegypti
Culex quinquefasciatus
Zika virus
Guadeloupe
vector competence
title Transmission potential of African, Asian and American Zika virus strains by Aedes aegypti and Culex quinquefasciatus from Guadeloupe (French West Indies)
title_full Transmission potential of African, Asian and American Zika virus strains by Aedes aegypti and Culex quinquefasciatus from Guadeloupe (French West Indies)
title_fullStr Transmission potential of African, Asian and American Zika virus strains by Aedes aegypti and Culex quinquefasciatus from Guadeloupe (French West Indies)
title_full_unstemmed Transmission potential of African, Asian and American Zika virus strains by Aedes aegypti and Culex quinquefasciatus from Guadeloupe (French West Indies)
title_short Transmission potential of African, Asian and American Zika virus strains by Aedes aegypti and Culex quinquefasciatus from Guadeloupe (French West Indies)
title_sort transmission potential of african asian and american zika virus strains by aedes aegypti and culex quinquefasciatus from guadeloupe french west indies
topic Aedes aegypti
Culex quinquefasciatus
Zika virus
Guadeloupe
vector competence
url https://www.tandfonline.com/doi/10.1080/22221751.2019.1615849
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