A point-of-care diagnostic for drug-induced liver injury using surface-enhanced Raman scattering lateral flow immunoassay

A point-of-care diagnostic for drug-induced liver injury using surface-enhanced Raman scattering lateral flow immunoassay

Abstract Paracetamol overdose (POD) is common, with approximately 100,000 cases attending UK hospitals annually. Timely antidote administration is crucial for patients at risk of developing acute liver failure. A rapid point-of-care (POC) assay is required to identify high-risk patients with fit-for...

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Main Authors: Sian Sloan-Dennison, Kathleen M. Scullion, Benjamin Clark, Paul Fineran, Joanne Mair, Stacey Laing, Neil C. Shand, Cicely Rathmell, David Creasey, Dieter Bingemann, Jonathan Faircloth, Mark Zieg, Elizabeth Varghese, Christopher J. Weir, James W. Dear, Karen Faulds, Duncan Graham
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-61600-9
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