Acute Kidney Injury in the Neonatal Period: Retrospective Data and Implications for Clinical Practice
<b>Background</b>: Neonates, particularly those born prematurely or with low birth weight, face an elevated risk of developing Acute Kidney Injury (AKI) due to various factors. Perinatal and maternal considerations, often linked to preterm delivery, contribute to this heightened risk. &l...
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| Format: | Article |
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MDPI AG
2025-07-01
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| Series: | Children |
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| Online Access: | https://www.mdpi.com/2227-9067/12/7/883 |
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| author | Meidad Greenberg Saray Sity-Harel Sydney Benchetrit Lewis Reisman Tali Zitman-Gal Daniel Erez Maysam Shehab Keren Cohen-Hagai |
| author_facet | Meidad Greenberg Saray Sity-Harel Sydney Benchetrit Lewis Reisman Tali Zitman-Gal Daniel Erez Maysam Shehab Keren Cohen-Hagai |
| author_sort | Meidad Greenberg |
| collection | DOAJ |
| description | <b>Background</b>: Neonates, particularly those born prematurely or with low birth weight, face an elevated risk of developing Acute Kidney Injury (AKI) due to various factors. Perinatal and maternal considerations, often linked to preterm delivery, contribute to this heightened risk. <b>Methods</b>: A retrospective study of neonates admitted to the intensive care unit at a single Israeli Hospital who were diagnosed as having AKI. The study includes follow-up data on these children. <b>Results</b>: During the study period, 971 neonates were admitted to the Pediatric Intensive Care Unit (PICU), and 47 cases had a documented diagnosis of AKI. Thirty-four of them had available long-term data and were included in this analysis. A total of 13 out of 26 subjects with available blood pressure measurements had high blood pressure for their age percentile compatible with the definition of hypertension, and 6 out of 34 (17.6%) had proteinuria. <b>Conclusions</b>: These findings underscore the importance of increased clinical awareness and structured long-term follow-up for neonates who experience AKI. |
| format | Article |
| id | doaj-art-26090ee3d6ca40f787ece4f013c0a074 |
| institution | DOAJ |
| issn | 2227-9067 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Children |
| spelling | doaj-art-26090ee3d6ca40f787ece4f013c0a0742025-08-20T02:45:38ZengMDPI AGChildren2227-90672025-07-0112788310.3390/children12070883Acute Kidney Injury in the Neonatal Period: Retrospective Data and Implications for Clinical PracticeMeidad Greenberg0Saray Sity-Harel1Sydney Benchetrit2Lewis Reisman3Tali Zitman-Gal4Daniel Erez5Maysam Shehab6Keren Cohen-Hagai7Department of Pediatrics, Meir Medical Center, 59 Tchernichovsky St., Kfar Saba 4428164, IsraelDepartment of Pediatrics, Meir Medical Center, 59 Tchernichovsky St., Kfar Saba 4428164, IsraelDepartment of Nephrology and Hypertension, Meir Medical Center, Kfar Saba 4428164, IsraelPediatric Nephrology Unit, Tel Aviv Sourasky Medical Center, Dana-Dwek Children’s Hospital, Tel Aviv 6423906, IsraelDepartment of Nephrology and Hypertension, Meir Medical Center, Kfar Saba 4428164, IsraelGray Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv 6997801, IsraelGray Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv 6997801, IsraelDepartment of Nephrology and Hypertension, Meir Medical Center, Kfar Saba 4428164, Israel<b>Background</b>: Neonates, particularly those born prematurely or with low birth weight, face an elevated risk of developing Acute Kidney Injury (AKI) due to various factors. Perinatal and maternal considerations, often linked to preterm delivery, contribute to this heightened risk. <b>Methods</b>: A retrospective study of neonates admitted to the intensive care unit at a single Israeli Hospital who were diagnosed as having AKI. The study includes follow-up data on these children. <b>Results</b>: During the study period, 971 neonates were admitted to the Pediatric Intensive Care Unit (PICU), and 47 cases had a documented diagnosis of AKI. Thirty-four of them had available long-term data and were included in this analysis. A total of 13 out of 26 subjects with available blood pressure measurements had high blood pressure for their age percentile compatible with the definition of hypertension, and 6 out of 34 (17.6%) had proteinuria. <b>Conclusions</b>: These findings underscore the importance of increased clinical awareness and structured long-term follow-up for neonates who experience AKI.https://www.mdpi.com/2227-9067/12/7/883acute kidney injuryneonatalchronic kidney disease |
| spellingShingle | Meidad Greenberg Saray Sity-Harel Sydney Benchetrit Lewis Reisman Tali Zitman-Gal Daniel Erez Maysam Shehab Keren Cohen-Hagai Acute Kidney Injury in the Neonatal Period: Retrospective Data and Implications for Clinical Practice Children acute kidney injury neonatal chronic kidney disease |
| title | Acute Kidney Injury in the Neonatal Period: Retrospective Data and Implications for Clinical Practice |
| title_full | Acute Kidney Injury in the Neonatal Period: Retrospective Data and Implications for Clinical Practice |
| title_fullStr | Acute Kidney Injury in the Neonatal Period: Retrospective Data and Implications for Clinical Practice |
| title_full_unstemmed | Acute Kidney Injury in the Neonatal Period: Retrospective Data and Implications for Clinical Practice |
| title_short | Acute Kidney Injury in the Neonatal Period: Retrospective Data and Implications for Clinical Practice |
| title_sort | acute kidney injury in the neonatal period retrospective data and implications for clinical practice |
| topic | acute kidney injury neonatal chronic kidney disease |
| url | https://www.mdpi.com/2227-9067/12/7/883 |
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