Adipokine imbalance and its role in the pathogenesis of novel coronavirus infection
The review summarizes and analyzes the results of major foreign studies on the role of adipokine imbalance in the development of a severe course and complications of novel coronavirus infection (COVID-19). Adipokines are biologically active compounds produced by adipose tissue cells and involved in...
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| Format: | Article |
| Language: | English |
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Siberian State Medical University (Tomsk)
2024-01-01
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| Series: | Бюллетень сибирской медицины |
| Subjects: | |
| Online Access: | https://bulletin.ssmu.ru/jour/article/view/5433 |
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| author | I. D. Bespalova U. M. Mitrichenko V. V. Kalyuzhin E. S. Koroleva Yu. I. Koshchavtseva D. S. Romanov D. E. Pershina |
| author_facet | I. D. Bespalova U. M. Mitrichenko V. V. Kalyuzhin E. S. Koroleva Yu. I. Koshchavtseva D. S. Romanov D. E. Pershina |
| author_sort | I. D. Bespalova |
| collection | DOAJ |
| description | The review summarizes and analyzes the results of major foreign studies on the role of adipokine imbalance in the development of a severe course and complications of novel coronavirus infection (COVID-19). Adipokines are biologically active compounds produced by adipose tissue cells and involved in the regulation of metabolism and the functioning of the immune system. Obesity is a proven risk factor for severe COVID-19 due to high hormonal and metabolic activity of visceral adipose tissue. A deep understanding of COVID-19 pathogenesis from the point of view of the role of adipokine imbalance in it can provide the grounds for the development of effective pathogenetic approaches to the prevention of a severe course and complications of novel coronavirus infection. |
| format | Article |
| id | doaj-art-25fa6b85da8749a5bb45f35621d1ed00 |
| institution | Kabale University |
| issn | 1682-0363 1819-3684 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Siberian State Medical University (Tomsk) |
| record_format | Article |
| series | Бюллетень сибирской медицины |
| spelling | doaj-art-25fa6b85da8749a5bb45f35621d1ed002025-08-20T03:37:41ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842024-01-0122416417310.20538/1682-0363-2023-4-164-1733042Adipokine imbalance and its role in the pathogenesis of novel coronavirus infectionI. D. Bespalova0U. M. Mitrichenko1V. V. Kalyuzhin2E. S. Koroleva3Yu. I. Koshchavtseva4D. S. Romanov5D. E. Pershina6Siberian State Medical UniversitySiberian State Medical UniversitySiberian State Medical UniversitySiberian State Medical UniversitySiberian State Medical UniversitySiberian State Medical UniversitySiberian State Medical UniversityThe review summarizes and analyzes the results of major foreign studies on the role of adipokine imbalance in the development of a severe course and complications of novel coronavirus infection (COVID-19). Adipokines are biologically active compounds produced by adipose tissue cells and involved in the regulation of metabolism and the functioning of the immune system. Obesity is a proven risk factor for severe COVID-19 due to high hormonal and metabolic activity of visceral adipose tissue. A deep understanding of COVID-19 pathogenesis from the point of view of the role of adipokine imbalance in it can provide the grounds for the development of effective pathogenetic approaches to the prevention of a severe course and complications of novel coronavirus infection.https://bulletin.ssmu.ru/jour/article/view/5433novel coronavirus infectionsars-cov-2metabolic syndromeobesityadipokinesadipokine imbalance |
| spellingShingle | I. D. Bespalova U. M. Mitrichenko V. V. Kalyuzhin E. S. Koroleva Yu. I. Koshchavtseva D. S. Romanov D. E. Pershina Adipokine imbalance and its role in the pathogenesis of novel coronavirus infection Бюллетень сибирской медицины novel coronavirus infection sars-cov-2 metabolic syndrome obesity adipokines adipokine imbalance |
| title | Adipokine imbalance and its role in the pathogenesis of novel coronavirus infection |
| title_full | Adipokine imbalance and its role in the pathogenesis of novel coronavirus infection |
| title_fullStr | Adipokine imbalance and its role in the pathogenesis of novel coronavirus infection |
| title_full_unstemmed | Adipokine imbalance and its role in the pathogenesis of novel coronavirus infection |
| title_short | Adipokine imbalance and its role in the pathogenesis of novel coronavirus infection |
| title_sort | adipokine imbalance and its role in the pathogenesis of novel coronavirus infection |
| topic | novel coronavirus infection sars-cov-2 metabolic syndrome obesity adipokines adipokine imbalance |
| url | https://bulletin.ssmu.ru/jour/article/view/5433 |
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