Machine learning-driven identification of critical gene programs and key transcription factors in migraine

Machine learning-driven identification of critical gene programs and key transcription factors in migraine

Abstract Background Migraine is a complex neurological disorder characterized by recurrent episodes of severe headaches. Although genetic factors have been implicated, the precise molecular mechanisms, particularly gene expression patterns in migraine-associated brain regions, remain unclear. This s...

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Bibliographic Details
Main Authors: Lei Zhang, Yujie Li, Yunhao Xu, Wei Wang, Guangyu Guo
Format: Article
Language:English
Published: BMC 2025-01-01
Series:The Journal of Headache and Pain
Subjects:
Migraine
Gene program
Random forest
Online Access:https://doi.org/10.1186/s10194-025-01950-3
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