Natural Products and Health Care Functions of <i>Inonotus obliquus</i>
With the increasing attention of modern medicine to natural medicinal agents, <i>Inonotus obliquus</i> (chaga), a macrofungus with remarkable medicinal value, has gradually garnered widespread academic interest. This paper reviews the primary bioactive components of <i>I. obliquus&...
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| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2025-04-01
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| Series: | Current Issues in Molecular Biology |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1467-3045/47/4/269 |
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| Summary: | With the increasing attention of modern medicine to natural medicinal agents, <i>Inonotus obliquus</i> (chaga), a macrofungus with remarkable medicinal value, has gradually garnered widespread academic interest. This paper reviews the primary bioactive components of <i>I. obliquus</i> in recent years, including polysaccharides, phenolic compounds, and triterpenoids, which exhibit diverse pharmacological effects such as antioxidant, anti-inflammatory, immunomodulatory, and antitumor activities. It further discusses how these bioactive components enhance human health and disease resistance through distinct biological mechanisms, such as the activation of antioxidant systems, regulation of immune responses, and modulation of apoptosis pathways. Additionally, the article explores the biosynthetic pathways of <i>I. obliquus</i> metabolites and their pharmacological relevance. Finally, we summarize the potential of <i>I. obliquus</i> as a natural medicinal resource and envisage its future applications in clinical drug development. This review aims to provide novel perspectives for the cultivation, utilization, and industrial-scale exploitation of <i>I. obliquus</i>. |
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| ISSN: | 1467-3037 1467-3045 |