The RNA M5C methyltransferase NSUN2 promotes progression of hepatocellular carcinoma by enhancing PKM2-mediated glycolysis
Abstract Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide. The 5-methylcytosine (m5C) RNA methyltransferase NSUN2 is involved in cell proliferation and metastasis and is upregulated in a variety of cancers. However, the biological function and regulatory mechanism of NSUN2-...
Saved in:
Main Authors: | Qin Qi, Rui Zhong, Yan Huang, Yong Tang, Xiao-wen Zhang, Chang Liu, Chun-fang Gao, Lin Zhou, Jian Yu, Lu-yi Wu |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2025-02-01
|
Series: | Cell Death and Disease |
Online Access: | https://doi.org/10.1038/s41419-025-07414-5 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
GP73-mediated secretion of PKM2 and GP73 promotes angiogenesis and M2-like macrophage polarization in hepatocellular carcinoma
by: Shujie Wang, et al.
Published: (2025-02-01) -
Nitidine chloride inhibits the progression of hepatocellular carcinoma by suppressing IGF2BP3 and modulates metabolic pathways in an m6A-dependent manner
by: Dan-dan Xiong, et al.
Published: (2025-02-01) -
FTO effects the proliferation, invasion, and glycolytic metabolism of colon cancer by regulating PKM2
by: Kongyan Zhang, et al.
Published: (2025-01-01) -
Isoacteoside alleviates hepatocellular carcinoma progression by inhibiting PDHB-mediated reprogramming of glucose metabolism
by: Lijun Zhao, et al.
Published: (2025-02-01) -
Risk factors of development of hepatocellular carcinoma
by: V. T. Ivashkin, et al.
Published: (2009-02-01)