A Case Report of Anti‐GD3 Antibody Positive Incomplete Miller‐Fisher Syndrome With Pyramidal Tract Symptoms
ABSTRACT Incomplete Miller‐Fisher syndrome (MFS) is a rare autoimmune disorder affecting the nervous system. In contrast to classical MFS, its clinical manifestations are often atypical and may be characterized by the absence of certain features, such as extraocular muscle paralysis and the loss of...
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| Format: | Article |
| Language: | English |
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Wiley
2025-02-01
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| Series: | Clinical Case Reports |
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| Online Access: | https://doi.org/10.1002/ccr3.70144 |
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| author | Zhaojiao Li Jun Li Lingchun Liu Jiajie Chen Xueye Mao Jing Yang Shu Yang Haixia Li Shan Li Qiang Meng |
| author_facet | Zhaojiao Li Jun Li Lingchun Liu Jiajie Chen Xueye Mao Jing Yang Shu Yang Haixia Li Shan Li Qiang Meng |
| author_sort | Zhaojiao Li |
| collection | DOAJ |
| description | ABSTRACT Incomplete Miller‐Fisher syndrome (MFS) is a rare autoimmune disorder affecting the nervous system. In contrast to classical MFS, its clinical manifestations are often atypical and may be characterized by the absence of certain features, such as extraocular muscle paralysis and the loss of tendon reflexes. The presence of anti‐GD3 antibodies is infrequently observed in these patients. This case report describes a patient diagnosed with incomplete MFS who exhibited positive anti‐GD3 antibody results and presented with pyramidal tract signs. This suggests that anti‐GD3 antibodies may play a role in the pathogenesis of some atypical forms of MFS, warranting attention in clinical practice. |
| format | Article |
| id | doaj-art-25e468dde66b428aa3a1cca4f1153d0c |
| institution | OA Journals |
| issn | 2050-0904 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Wiley |
| record_format | Article |
| series | Clinical Case Reports |
| spelling | doaj-art-25e468dde66b428aa3a1cca4f1153d0c2025-08-20T02:15:51ZengWileyClinical Case Reports2050-09042025-02-01132n/an/a10.1002/ccr3.70144A Case Report of Anti‐GD3 Antibody Positive Incomplete Miller‐Fisher Syndrome With Pyramidal Tract SymptomsZhaojiao Li0Jun Li1Lingchun Liu2Jiajie Chen3Xueye Mao4Jing Yang5Shu Yang6Haixia Li7Shan Li8Qiang Meng9Department of Neurology The First People's Hospital of Yunnan Province, The Affiliated Hospital of Kunming University of Science and Technology Kunming ChinaDepartment of Neurology The First People's Hospital of Yunnan Province, The Affiliated Hospital of Kunming University of Science and Technology Kunming ChinaDepartment of Neurology The First People's Hospital of Yunnan Province, The Affiliated Hospital of Kunming University of Science and Technology Kunming ChinaDepartment of Neurology The First People's Hospital of Yunnan Province, The Affiliated Hospital of Kunming University of Science and Technology Kunming ChinaDepartment of Neurology The First People's Hospital of Yunnan Province, The Affiliated Hospital of Kunming University of Science and Technology Kunming ChinaDepartment of Neurology The First People's Hospital of Yunnan Province, The Affiliated Hospital of Kunming University of Science and Technology Kunming ChinaDepartment of Neurology The First People's Hospital of Yunnan Province, The Affiliated Hospital of Kunming University of Science and Technology Kunming ChinaDepartment of Neurology The First People's Hospital of Yunnan Province, The Affiliated Hospital of Kunming University of Science and Technology Kunming ChinaDepartment of Neurology The First People's Hospital of Yunnan Province, The Affiliated Hospital of Kunming University of Science and Technology Kunming ChinaDepartment of Neurology The First People's Hospital of Yunnan Province, The Affiliated Hospital of Kunming University of Science and Technology Kunming ChinaABSTRACT Incomplete Miller‐Fisher syndrome (MFS) is a rare autoimmune disorder affecting the nervous system. In contrast to classical MFS, its clinical manifestations are often atypical and may be characterized by the absence of certain features, such as extraocular muscle paralysis and the loss of tendon reflexes. The presence of anti‐GD3 antibodies is infrequently observed in these patients. This case report describes a patient diagnosed with incomplete MFS who exhibited positive anti‐GD3 antibody results and presented with pyramidal tract signs. This suggests that anti‐GD3 antibodies may play a role in the pathogenesis of some atypical forms of MFS, warranting attention in clinical practice.https://doi.org/10.1002/ccr3.70144anti‐GD3 antibodycase reportMiller‐Fisher syndromenovel coronavirus vaccinepyramidal tract symptom |
| spellingShingle | Zhaojiao Li Jun Li Lingchun Liu Jiajie Chen Xueye Mao Jing Yang Shu Yang Haixia Li Shan Li Qiang Meng A Case Report of Anti‐GD3 Antibody Positive Incomplete Miller‐Fisher Syndrome With Pyramidal Tract Symptoms Clinical Case Reports anti‐GD3 antibody case report Miller‐Fisher syndrome novel coronavirus vaccine pyramidal tract symptom |
| title | A Case Report of Anti‐GD3 Antibody Positive Incomplete Miller‐Fisher Syndrome With Pyramidal Tract Symptoms |
| title_full | A Case Report of Anti‐GD3 Antibody Positive Incomplete Miller‐Fisher Syndrome With Pyramidal Tract Symptoms |
| title_fullStr | A Case Report of Anti‐GD3 Antibody Positive Incomplete Miller‐Fisher Syndrome With Pyramidal Tract Symptoms |
| title_full_unstemmed | A Case Report of Anti‐GD3 Antibody Positive Incomplete Miller‐Fisher Syndrome With Pyramidal Tract Symptoms |
| title_short | A Case Report of Anti‐GD3 Antibody Positive Incomplete Miller‐Fisher Syndrome With Pyramidal Tract Symptoms |
| title_sort | case report of anti gd3 antibody positive incomplete miller fisher syndrome with pyramidal tract symptoms |
| topic | anti‐GD3 antibody case report Miller‐Fisher syndrome novel coronavirus vaccine pyramidal tract symptom |
| url | https://doi.org/10.1002/ccr3.70144 |
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