The role of epigenetic modification in tumorigenesis and progression of pituitary adenomas: a systematic review of the literature.

The role of epigenetic modification in tumorigenesis and progression of pituitary adenomas: a systematic review of the literature.

<h4>Background</h4>Pituitary adenomas (PAs) are commonly occurring neoplasms with diverse endocrine and neurological effects. Although somatic gene mutations are uncommon in sporadic PAs, recent studies lend support to epigenetic modification as a potential cause of tumorigenesis and tum...

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Bibliographic Details
Main Authors: Matthew Pease, Chao Ling, William J Mack, Kai Wang, Gabriel Zada
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0082619
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